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Setd4tm2.1(cre/ERT2)Wjy
Targeted Allele Detail
Summary
Symbol: Setd4tm2.1(cre/ERT2)Wjy
Name: SET domain containing 4; targeted mutation 2.1, Wei-Jun Yang
MGI ID: MGI:6822323
Synonyms: SETD4-CreERT2
Gene: Setd4  Location: Chr16:93380345-93400951 bp, - strand  Genetic Position: Chr16, 54.52 cM
Alliance: Setd4tm2.1(cre/ERT2)Wjy page
Mutation
origin
Germline Transmission:  Earliest citation of germline transmission: J:314227
Parent Cell Line:  Not Specified (ES Cell)
Strain of Origin:  Not Specified
Mutation
description
Allele Type:    Targeted (Inducible, Recombinase)
Inducer:    tamoxifen
Mutation:    Insertion
 
Setd4tm2.1(cre/ERT2)Wjy expression driven by 1 gene
 
Mutation details: By homologous recombination in ES cells, a V5-P2A-CreERT2-WPRE-polyA cassette was inserted after the exon 12 of the mouse Setd4 gene. Resulted chimeras were crossed with Flp mice to remove the neo selection cassette. (J:314227)
Recombinase
activity
Activity:
 Tissue activity of this recombinase allele
Driver: Setd4 (mouse)
Summary of all recombinase alleles driven by Setd4.
 

Find Mice (IMSR)
Mouse strains and cell lines available from the International Mouse Strain Resource (IMSR)
Carrying this Mutation:  Mouse Strains: 0 strains available      Cell Lines: 0 lines available
Carrying any Setd4 Mutation:  30 strains or lines available
References
Original:  J:314227 Tian JZ, et al., SETD4-expressing cells contribute to pancreatic development and response to cerulein induced pancreatitis injury. Sci Rep. 2021 Jun 15;11(1):12614
All:  3 reference(s)
Contributing Projects:
Mouse Genome Database (MGD), Gene Expression Database (GXD), Mouse Models of Human Cancer database (MMHCdb) (formerly Mouse Tumor Biology (MTB)), Gene Ontology (GO)
Citing These Resources
Funding Information
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11/12/2024
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