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Tg(Prkcd-cre)PIto
Transgene Detail
Summary
Symbol: Tg(Prkcd-cre)PIto
Name: transgene insertion P, Shigeyoshi Itohara
MGI ID: MGI:6827391
Synonyms: Pkcd-Cre
Transgene: Tg(Prkcd-cre)PIto  Location: unknown  
Alliance: Tg(Prkcd-cre)PIto page
Transgene
origin
Strain of Origin:  Not Specified
Transgene
description
Transgene Type:    Transgenic (Recombinase)
Mutation:    Insertion
 
Tg(Prkcd-cre)PIto expression driven by 1 gene
 
Mutation detailsTg construct was created by modifying mouse BAC clone to insert the nuclear localization signal (NLS) Cre-pA cassette and FRT-Amp-FRT sequence into the translational initiation site of the Prkcd gene. The Amp sequence in the obtained BAC construct was removed by flp/FRT recombination in bacteria. Among the multiple lines obtained, a line (P) with high selectivity of recombination in the dorsal thalamic nuclei was selected. (J:254126)
Recombinase
activity
Activity:
 Tissue activity of this recombinase allele
Driver: Prkcd (mouse)
Summary of all recombinase alleles driven by Prkcd.
 

Find Mice (IMSR)
Mouse strains and cell lines available from the International Mouse Strain Resource (IMSR)
Carrying this Mutation:  Mouse Strains: 1 strain available      Cell Lines: 0 lines available
References
Original:  J:254126 Zhang Q, et al., Netrin-G1 regulates fear-like and anxiety-like behaviors in dissociable neural circuits. Sci Rep. 2016 Jun 27;6:28750
All:  2 reference(s)

Contributing Projects:
Mouse Genome Database (MGD), Gene Expression Database (GXD), Mouse Models of Human Cancer database (MMHCdb) (formerly Mouse Tumor Biology (MTB)), Gene Ontology (GO)
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last database update
11/12/2024
MGI 6.24
The Jackson Laboratory