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Tg(Pomc-dre)#Jcbr
Transgene Detail
Summary
Symbol: Tg(Pomc-dre)#Jcbr
Name: transgene insertion, Jens C Bruning
MGI ID: MGI:6828609
Synonyms: POMCDre
Transgene: Tg(Pomc-dre)#Jcbr  Location: unknown  
Alliance: Tg(Pomc-dre)#Jcbr page
Transgene
origin
Strain of Origin:  Not Specified
Transgene
description
Transgene Type:    Transgenic (Recombinase)
Mutation:    Insertion
 
Tg(Pomc-dre)#Jcbr expression driven by 1 gene
 
Mutation details: Using Red/ET recombination, the sequence encoding Dre recombinase together with a kanamycin/neomycin resistance cassette replaced the ATG start codon of the mouse Pomc gene of RP11-124K7 BAC clone. Five of seven transgenic lines showed similar specificity in the ARC and in the anterior and intermediate lobes of the pituitary. Line numbers were not indicated. The pound symbol (#) is used when no line is specified and/or lines are pooled. (J:314806)
Recombinase
activity
Activity:
 Tissue activity of this recombinase allele
Driver: Pomc (mouse)
Summary of all recombinase alleles driven by Pomc.
 

Find Mice (IMSR)
Mouse strains and cell lines available from the International Mouse Strain Resource (IMSR)
Carrying this Mutation:  Mouse Strains: 0 strains available      Cell Lines: 0 lines available
References
Original:  J:314806 Biglari N, et al., Functionally distinct POMC-expressing neuron subpopulations in hypothalamus revealed by intersectional targeting. Nat Neurosci. 2021 Jul;24(7):913-929
All:  1 reference(s)
Contributing Projects:
Mouse Genome Database (MGD), Gene Expression Database (GXD), Mouse Models of Human Cancer database (MMHCdb) (formerly Mouse Tumor Biology (MTB)), Gene Ontology (GO)
Citing These Resources
Funding Information
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Send questions and comments to User Support. 		last database update
11/12/2024
MGI 6.24 		The Jackson Laboratory