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Atoh1em1(cre)Zyliu
Endonuclease-mediated Allele Detail
Summary
Symbol: Atoh1em1(cre)Zyliu
Name: atonal bHLH transcription factor 1; endonuclease-mediated mutation 1, Zhiyong Liu
MGI ID: MGI:6856836
Synonyms: Atoh13*HA-P2A-Cre
Gene: Atoh1  Location: Chr6:64706109-64708229 bp, + strand  Genetic Position: Chr6, 30.03 cM
Alliance: Atoh1em1(cre)Zyliu page
Mutation
origin
Strain of Origin:  C57BL/6 x DBA/2
Mutation
description
Allele Type:    Endonuclease-mediated (Recombinase)
Mutation:    Insertion
 
Atoh1em1(cre)Zyliu expression driven by 1 gene
 
Mutation details: Using CRISPR/Cas9 technology, three hemagglutinin (HA) tags, a P2A ribosomal skip cleavage peptide sequence, and a cre recombinase were inserted immediately before the stop codon of the atonal bHLH transcription factor 1 (Atoh1) gene. (J:326361)
Recombinase
activity
Activity:
 Tissue activity of this recombinase allele
Driver: Atoh1 (mouse)
Summary of all recombinase alleles driven by Atoh1.
 

Expression
In Mice Carrying this Mutation: 125 assay results
Find Mice (IMSR)
Mouse strains and cell lines available from the International Mouse Strain Resource (IMSR)
Carrying this Mutation:  Mouse Strains: 1 strain available      Cell Lines: 0 lines available
Carrying any Atoh1 Mutation:  37 strains or lines available
References
Original:  J:326361 Li S, et al., Fate-mapping analysis of cochlear cells expressing Atoh1 mRNA via a new Atoh1(3*HA-P2A-Cre) knockin mouse strain. Dev Dyn. 2022 Jul;251(7):1156-1174
All:  2 reference(s)
Contributing Projects:
Mouse Genome Database (MGD), Gene Expression Database (GXD), Mouse Models of Human Cancer database (MMHCdb) (formerly Mouse Tumor Biology (MTB)), Gene Ontology (GO)
Citing These Resources
Funding Information
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Send questions and comments to User Support. 		last database update
11/12/2024
MGI 6.24 		The Jackson Laboratory