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Gene Expression Data
Assay Details
Assay
Reference: J:158688 Seshadri S, et al., Disrupted-in-Schizophrenia-1 expression is regulated by beta-site amyloid precursor protein cleaving enzyme-1-neuregulin cascade. Proc Natl Acad Sci U S A. 2010 Mar 23;107(12):5622-7
Assay type: Western blot
MGI Accession ID: MGI:6860638
Gene symbol: Disc1
Gene name: disrupted in schizophrenia 1
Results
Image: 3A DISC1 ©

 Sample Information Bands Other Sample Information
Lane AgeStructure 130 kDa 105 kDa 100 kDa Genetic BackgroundMutant Allele(s)Sex
NRG1+/- P0 TS27: cerebral cortex Present (a) Present (b) Present (b) involves: 129P2/OlaHsd Nrg1tm1Cbm/Nrg1+Not Specified
WT P0 TS27: cerebral cortex Present Present Present involves: 129P2/OlaHsd Not Specified
Notes:
(a) There is a 23.6% decrease in expression compared to wild-type.
(b) Band strength in the heterozygote is the same as in wild-type.
Contributing Projects:
Mouse Genome Database (MGD), Gene Expression Database (GXD), Mouse Models of Human Cancer database (MMHCdb) (formerly Mouse Tumor Biology (MTB)), Gene Ontology (GO)
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09/17/2024
MGI 6.24 		The Jackson Laboratory