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Gene Expression Data
Assay Details
Assay
Reference: J:118243 Fan X, et al., Estrogen receptor beta expression in the embryonic brain regulates development of calretinin-immunoreactive GABAergic interneurons. Proc Natl Acad Sci U S A. 2006 Dec 19;103(51):19338-43
Assay type: Immunohistochemistry
MGI Accession ID: MGI:6861868
Gene symbol: Calb2
Gene name: calbindin 2
Antibody: Anti-Calretinin 7697
Detection system: Biotinylated secondary antibody/[Strept]avidin coupled to horseradish peroxidase
Results
Specimen 4A: embryonic day 18.5 (more )
Structure Level Pattern Image Note
TS26: thalamic nucleus Strong Regionally restricted 4A Strong expression in densely packed cells mainly localized in thalamic nuclei including anterior thalamic nucleus and paraventricular thalamic nucleus.
TS26: paraventricular thalamic nucleus Strong 4A
TS26: dentate gyrus Strong 4A
Specimen 4B: embryonic day 18.5 (more )
Structure Level Pattern Image Note
TS26: dentate gyrus Present 4B
TS26: medial habenular nucleus Present 4B
TS26: paraventricular thalamic nucleus Present 4B
TS26: reticular thalamic nucleus Present 4B
Specimen 4C: embryonic day 18.5 (more )
Structure Level Pattern Image Note
TS26: dentate gyrus Strong 4C
TS26: amygdala Strong Regionally restricted 4C Strong expression in upper migrating stream, including those from parafascicular nucleus to either lateral posterior thalamic nucleus or pretectal area, and in downward migrating streams from parafascicular nucleus to either lateral hypothalamic areas or basomedial amygdaloid nucleus.
TS26: hypothalamus lateral zone Strong Regionally restricted 4C Strong expression in upper migrating stream, including those from parafascicular nucleus to either lateral posterior thalamic nucleus or pretectal area, and in downward migrating streams from parafascicular nucleus to either lateral hypothalamic areas or basomedial amygdaloid nucleus.
TS26: parafascicular nucleus Strong Regionally restricted 4C Strong expression in upper migrating stream, including those from parafascicular nucleus to either lateral posterior thalamic nucleus or pretectal area, and in downward migrating streams from parafascicular nucleus to either lateral hypothalamic areas or basomedial amygdaloid nucleus.
TS26: pretectum Strong Regionally restricted 4C Strong expression in upper migrating stream, including those from parafascicular nucleus to either lateral posterior thalamic nucleus or pretectal area, and in downward migrating streams from parafascicular nucleus to either lateral hypothalamic areas or basomedial amygdaloid nucleus.
TS26: thalamic nucleus Strong Regionally restricted 4C Strong expression in upper migrating stream, including those from parafascicular nucleus to either lateral posterior thalamic nucleus or pretectal area, and in downward migrating streams from parafascicular nucleus to either lateral hypothalamic areas or basomedial amygdaloid nucleus.
Specimen 5A: embryonic day 16.5 (more )
Structure Level Pattern Image Note
TS24: amygdala Present 5A
TS24: dentate gyrus Present 5A
TS24: parafascicular nucleus Present 5A
TS24: pretectum Present 5A
TS24: thalamic nucleus Present 5A
Specimen 5B: embryonic day 16.5; Esr2tm1Unc/Esr2tm1Unc (more )
Structure Level Pattern Image Note
TS24: amygdala Weak 5B Expression markedly lower in parafascicular nucleus, dentate gyrus, and amygdala region.
TS24: dentate gyrus Weak 5B Expression markedly lower in parafascicular nucleus, dentate gyrus, and amygdala region.
TS24: parafascicular nucleus Weak 5B Expression markedly lower in parafascicular nucleus, dentate gyrus, and amygdala region.
TS24: pretectum Weak 5B Expression markedly lower in parafascicular nucleus, dentate gyrus, and amygdala region.
TS24: thalamic nucleus Weak 5B Expression markedly lower in parafascicular nucleus, dentate gyrus, and amygdala region.
Specimen 5C: embryonic day 16.5 (more )
Structure Level Pattern Image Note
TS24: parafascicular nucleus Present 5C
Specimen 5D: embryonic day 16.5; Esr2tm1Unc/Esr2tm1Unc (more )
Structure Level Pattern Image Note
TS24: parafascicular nucleus Weak 5D
Specimen 5E: embryonic day 18.5 (more )
Structure Level Pattern Image Note
TS26: paraventricular thalamic nucleus Present 5E
TS26: thalamic nucleus Present 5E
Specimen 5F: embryonic day 18.5; Esr2tm1Unc/Esr2tm1Unc (more )
Structure Level Pattern Image Note
TS26: paraventricular thalamic nucleus Weak 5F Expression much reduced compared with wild type littermates.
TS26: thalamic nucleus Weak 5F Expression much reduced compared with wild type littermates.
Specimen 5G: embryonic day 18.5 (more )
Structure Level Pattern Image Note
TS26: paraventricular thalamic nucleus Present 5G
TS26: thalamic nucleus Present 5G
Specimen 5H: embryonic day 18.5; Esr2tm1Unc/Esr2tm1Unc (more )
Structure Level Pattern Image Note
TS26: paraventricular thalamic nucleus Weak 5H Expression much reduced compared with wild type littermates.
TS26: thalamic nucleus Weak 5H Expression much reduced compared with wild type littermates.
Specimen 5I: embryonic day 18.5 (more )
Structure Level Pattern Image Note
TS26: medial habenular nucleus Present 5I
TS26: paraventricular thalamic nucleus Present 5I
Specimen 5J: embryonic day 18.5; Esr2tm1Unc/Esr2tm1Unc (more )
Structure Level Pattern Image Note
TS26: medial habenular nucleus Weak 5J Expression much reduced compared with wild type littermates.
TS26: paraventricular thalamic nucleus Weak 5J Expression much reduced compared with wild type littermates.
Specimen 5K: embryonic day 18.5 (more )
Structure Level Pattern Image Note
TS26: medial habenular nucleus Present 5K
TS26: paraventricular thalamic nucleus Present 5K
Specimen 5L: embryonic day 18.5; Esr2tm1Unc/Esr2tm1Unc (more )
Structure Level Pattern Image Note
TS26: medial habenular nucleus Weak 5L Expression much reduced compared with wild type littermates.
TS26: paraventricular thalamic nucleus Weak 5L Expression much reduced compared with wild type littermates.
Specimen E18.5 not shown: embryonic day 18.5; Esr2tm1Unc/Esr2tm1Unc (more )
Structure Level Pattern Image Note
TS26: amygdala Weak Expression much reduced compared with wild type littermates.
TS26: dentate gyrus Weak Expression much reduced compared with wild type littermates.
TS26: hypothalamus Weak Expression much reduced compared with wild type littermates.
TS26: reticular thalamic nucleus Weak Expression much reduced compared with wild type littermates.
Contributing Projects:
Mouse Genome Database (MGD), Gene Expression Database (GXD), Mouse Models of Human Cancer database (MMHCdb) (formerly Mouse Tumor Biology (MTB)), Gene Ontology (GO)
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06/12/2024
MGI 6.13 		The Jackson Laboratory