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Cnptm1.1(icre)Htak
Targeted Allele Detail
Summary
Symbol: Cnptm1.1(icre)Htak
Name: 2',3'-cyclic nucleotide 3' phosphodiesterase; targeted mutation 1.1, Hirohide Takebayashi
MGI ID: MGI:6865676
Synonyms: CnpiCre
Gene: Cnp  Location: Chr11:100465765-100472565 bp, + strand  Genetic Position: Chr11, 63.47 cM
Alliance: Cnptm1.1(icre)Htak page
Mutation
origin
Germline Transmission:  Earliest citation of germline transmission: J:319558
Parent Cell Line:  Not Specified (ES Cell)
Strain of Origin:  Not Specified
Mutation
description
Allele Type:    Targeted (Recombinase)
Mutation:    Insertion
 
Cnptm1.1(icre)Htak expression driven by 1 gene
 
Mutation details: The targeting construct inserted an improved cre recombinase gene (icre) at the translation initiation site in exon 2. Flp-mediated recombination removed the FRT-flanked neomycin resistance cassette inserted downstream of the recombinase gene. (J:319558)
Recombinase
activity
Activity:
 Tissue activity of this recombinase allele
Driver: Cnp (mouse)
Summary of all recombinase alleles driven by Cnp.
 

Find Mice (IMSR)
Mouse strains and cell lines available from the International Mouse Strain Resource (IMSR)
Carrying this Mutation:  Mouse Strains: 0 strains available      Cell Lines: 0 lines available
Carrying any Cnp Mutation:  27 strains or lines available
References
Original:  J:319558 Bizen N, et al., Ddx20, an Olig2 binding factor, governs the survival of neural and oligodendrocyte progenitor cells via proper Mdm2 splicing and p53 suppression. Cell Death Differ. 2022;
All:  1 reference(s)
Contributing Projects:
Mouse Genome Database (MGD), Gene Expression Database (GXD), Mouse Models of Human Cancer database (MMHCdb) (formerly Mouse Tumor Biology (MTB)), Gene Ontology (GO)
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Funding Information
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Send questions and comments to User Support. 		last database update
11/19/2024
MGI 6.24 		The Jackson Laboratory