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Gene Expression Data
Assay Details
Assay
Reference: J:316530 Uddin MK, et al., Foxc2 in pharyngeal arch mesenchyme is important for aortic arch artery remodelling and ventricular septum formation. Biomed Res. 2015;36(4):235-45
Assay type: Immunohistochemistry
MGI Accession ID: MGI:6879490
Gene symbol: Foxc2
Gene name: forkhead box C2
Antibody: Foxc2 antibody
Detection system: Secondary antibody coupled to Alexa Fluor 488
Results
Specimen 3A: embryonic day 10.5; Foxc2tm1.1Miu/Foxc2tm1.1Miu (more )
Structure Level Pattern Image Note
TS17: 4th branchial arch Present Regionally restricted 3A

Specimen 3B/C: embryonic day 10.5; Foxc2tm1.1Miu/Foxc2tm1.1Miu (more )
Structure Level Pattern Image Note
TS17: 4th arch artery Strong Regionally restricted 3C , 3B Strong expression in the endothelium of left fourth pharyngeal artery.
TS17: 4th branchial arch mesenchyme Strong Regionally restricted 3C , 3B Strong expression in mesenchymal cells surrounding the endothelium of left fourth pharyngeal artery.

Specimen 3D: embryonic day 10.5; Foxc2tm1.1Miu/Foxc2tm1.1Miu, Nkx2-5tm1(cre)Rjs/Nkx2-5+ (more )
Note: Conditional mutant.
Structure Level Pattern Image Note
TS17: 4th branchial arch Absent 3D

Specimen 3E/F: embryonic day 10.5; Foxc2tm1.1Miu/Foxc2tm1.1Miu, Nkx2-5tm1(cre)Rjs/Nkx2-5+ (more )
Note: Conditional mutant.
Structure Level Pattern Image Note
TS17: 4th arch artery Absent 3F , 3E Expression deleted in endothelium of left fourth pharyngeal artery.
TS17: 4th branchial arch mesenchyme Absent 3F , 3E Expression deleted in mesenchyme surrounding endothelium of left fourth pharyngeal artery.

Specimen 3G: embryonic day 10.5; Foxc2tm1.1Miu/Foxc2tm1.1Miu, Tg(Tek-cre)1Ywa/0 (more )
Note: Conditional mutant.
Structure Level Pattern Image Note
TS17: 4th branchial arch Present Regionally restricted 3G

Specimen 3H/I: embryonic day 10.5; Foxc2tm1.1Miu/Foxc2tm1.1Miu, Tg(Tek-cre)1Ywa/0 (more )
Note: Conditional mutant.
Structure Level Pattern Image Note
TS17: 4th arch artery Absent 3H , 3I Expression deleted in endothelium of left fourth pharyngeal artery compared to controls,.
TS17: 4th branchial arch mesenchyme Present Regionally restricted 3H , 3I Expression unaffected in mesenchymal cells surrounding endothelium of left fourth pharyngeal artery compared to controls,.


Contributing Projects:
Mouse Genome Database (MGD), Gene Expression Database (GXD), Mouse Models of Human Cancer database (MMHCdb) (formerly Mouse Tumor Biology (MTB)), Gene Ontology (GO)
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last database update
09/17/2024
MGI 6.24
The Jackson Laboratory