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Pgrem1(flpo)Shah
Endonuclease-mediated Allele Detail
Summary
Symbol: Pgrem1(flpo)Shah
Name: progesterone receptor; endonuclease-mediated mutation 1, Nirao Shah
MGI ID: MGI:6885881
Synonyms: PRFlpo
Gene: Pgr  Location: Chr9:8899834-8968612 bp, + strand  Genetic Position: Chr9, 2.46 cM
Alliance: Pgrem1(flpo)Shah page
Mutation
origin
Strain of Origin:  C57BL/6J
Mutation
description
Allele Type:    Endonuclease-mediated (Recombinase)
Mutation:    Insertion
 
Pgrem1(flpo)Shah expression driven by 1 gene
 
Mutation details: Using CRISPR/Cas9-mediated homologous recombination, the 2A-Flpo was inserted into the 3'UTR in exon 8 of the Pgr gene. (J:321365)
Recombinase
activity
Activity:
 Tissue activity of this recombinase allele
Driver: Pgr (mouse)
Summary of all recombinase alleles driven by Pgr.
 

Expression
In Mice Carrying this Mutation: 2 assay results
Find Mice (IMSR)
Mouse strains and cell lines available from the International Mouse Strain Resource (IMSR)
Carrying this Mutation:  Mouse Strains: 1 strain available      Cell Lines: 0 lines available
Carrying any Pgr Mutation:  75 strains or lines available
References
Original:  J:321365 Knoedler JR, et al., A functional cellular framework for sex and estrous cycle-dependent gene expression and behavior. Cell. 2022 Feb 17;185(4):654-671.e22
All:  1 reference(s)
Contributing Projects:
Mouse Genome Database (MGD), Gene Expression Database (GXD), Mouse Models of Human Cancer database (MMHCdb) (formerly Mouse Tumor Biology (MTB)), Gene Ontology (GO)
Citing These Resources
Funding Information
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Send questions and comments to User Support. 		last database update
11/12/2024
MGI 6.24 		The Jackson Laboratory