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Lyz2em3(cre)Smoc
Endonuclease-mediated Allele Detail
Summary
Symbol: Lyz2em3(cre)Smoc
Name: lysozyme 2; endonuclease-mediated mutation 3, Shanghai Model Organisms Center
MGI ID: MGI:6887678
Synonyms: C57BL/6-Lyz2em1(Cre)Smoc, Lysm-Cre
Gene: Lyz2  Location: Chr10:117113446-117118177 bp, - strand  Genetic Position: Chr10, 65.34 cM
Alliance: Lyz2em3(cre)Smoc page
Mutation
origin
Strain of Origin:  C57BL/6
Mutation
description
Allele Type:    Endonuclease-mediated (Recombinase)
Mutation:    Insertion
 
Lyz2em3(cre)Smoc expression driven by 1 gene
    CRISPR/Cas9 technology inserted a cre expression cassette into the gene. (J:238766, J:321587)
Recombinase
activity
Activity:
 Tissue activity of this recombinase allele
Driver: Lyz2 (mouse)
Summary of all recombinase alleles driven by Lyz2.
 

Find Mice (IMSR)
Mouse strains and cell lines available from the International Mouse Strain Resource (IMSR)
Carrying this Mutation:  Mouse Strains: 0 strains available      Cell Lines: 0 lines available
Carrying any Lyz2 Mutation:  40 strains or lines available
References
Original:  J:321587 Ai K, et al., Methyl-CpG-binding domain protein 2 contributes to renal fibrosis through promoting polarized M1 macrophages. Cell Death Dis. 2022 Feb 8;13(2):125
All:  8 reference(s)
Contributing Projects:
Mouse Genome Database (MGD), Gene Expression Database (GXD), Mouse Models of Human Cancer database (MMHCdb) (formerly Mouse Tumor Biology (MTB)), Gene Ontology (GO)
Citing These Resources
Funding Information
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Send questions and comments to User Support. 		last database update
08/02/2024
MGI 6.24 		The Jackson Laboratory