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Gene Expression Data
Assay Details
Assay
Reference: J:308975 Takenoshita M, et al., Cell lineage- and expression-based inference of the roles of forkhead box transcription factor Foxc2 in craniofacial development. Dev Dyn. 2021 Aug;250(8):1125-1139
Assay type: RNA in situ
MGI Accession ID: MGI:7261296
Gene symbol: Foxc2
Gene name: forkhead box C2
Probe: Foxc2 probe5
Probe preparation: Antisense labelled with digoxigenin RNA
Visualized with: Alkaline phosphatase
Results
Specimen 4A: embryonic day 8.5 (more )
Structure Level Pattern Image Note
TS13: head mesenchyme Present 4A
TS13: head somite Present 4A

Specimen 4B: embryonic day 9.5 (more )
Structure Level Pattern Image Note
TS15: head mesenchyme Present Regionally restricted 4B Expression in mesenchyme under brain.
TS15: eye mesenchyme Present Regionally restricted 4B Expression in mesenchyme at periphery of eye.
TS15: 1st branchial arch Present Regionally restricted 4B Expression in proximal portion of first an second pharyngeal arches, corresponding to middle ear ossicle-forming area.
TS15: 2nd branchial arch Present Regionally restricted 4B Expression in proximal portion of first an second pharyngeal arches, corresponding to middle ear ossicle-forming area.
TS15: forelimb bud mesenchyme Absent 4B

Specimen 4C: embryonic day 10.5 (more )
Structure Level Pattern Image Note
TS17: head mesenchyme Present Regionally restricted 4C Expression in mesenchyme under brain.
TS17: eye mesenchyme Present Regionally restricted 4C Expression in mesenchyme at periphery of eye.
TS17: 1st branchial arch Present Regionally restricted 4C Expression in proximal portion of first an second pharyngeal arches, corresponding to middle ear ossicle-forming area.
TS17: 2nd branchial arch Present Regionally restricted 4C Expression in proximal portion of first an second pharyngeal arches, corresponding to middle ear ossicle-forming area.
TS17: forelimb bud mesenchyme Absent 4C

Specimen 4D: embryonic day 10.5 (more )
Structure Level Pattern Image Note
TS17: head mesenchyme Present Regionally restricted 4D Expression in mesenchyme forming cranial base.
TS17: branchial arch mesenchyme Present 4D
TS17: middle ear mesenchyme Present 4D
TS17: forelimb bud mesenchyme Absent 4D

Specimen 4E: embryonic day 10.5 (more )
Structure Level Pattern Image Note
TS17: head Present 4E Authors report expression in a similar manner to that of Foxc1.

Specimen 5A: embryonic day 12.5 (more )
Structure Level Pattern Image Note
TS20: cranium Present Regionally restricted 5A Expression in cranial base.
TS20: nose Present Regionally restricted 5A Expression in nasal capsule.
TS20: otic capsule Present 5A

Specimen 5B: embryonic day 12.5 (more )
Structure Level Pattern Image Note
TS20: cranium Present Regionally restricted 5B Expression in cranial base.
TS20: tongue epithelium Present 5B
TS20: tongue muscle Present Regionally restricted 5B Expression in genioglossus-forming area.
TS20: Meckel's cartilage Present 5B

Specimen 5C: embryonic day 12.5 (more )
Structure Level Pattern Image Note
TS20: nose Present Regionally restricted 5C Expression in nasal capsule.
TS20: otic capsule Present 5C
TS20: middle ear mesenchyme Present Regionally restricted 5C Expression in auditory ossicles.

Specimen 5G: embryonic day 14.5 (more )
Structure Level Pattern Image Note
TS22: chondrocranium Present Regionally restricted 5G Similar pattern of expression in cartilage of chondrocranium as seen at E12.5.
TS22: perichondrium Strong Regionally restricted 5G Vigorous expression in perichondrium.

Specimen 5H: embryonic day 14.5 (more )
Structure Cell Type Level Pattern Image Note
TS22: chondrocranium chondrocyte Present 5H
TS22: tongue epithelium Present 5H

Specimen 5I: embryonic day 14.5 (more )
Structure Level Pattern Image Note
TS22: chondrocranium Present Regionally restricted 5I Similar pattern of expression in cartilage of chondrocranium as seen at E12.5.

Specimen 7A: embryonic day 12.5 (more )
Structure Level Pattern Image Note
TS20: palatal shelf Absent 7A
TS20: tongue epithelium Present 7A
TS20: tongue muscle Present Regionally restricted 7A Expression in genioglossus-forming area.
TS20: Meckel's cartilage Present 7A
TS20: head mesenchyme Present Regionally restricted 7A Expression in mesenchyme between genioglossus and Meckel;s cartilage.

Specimen 10A: embryonic day 11.5 (more )
Structure Level Pattern Image Note
TS19: tongue Present 10A


Contributing Projects:
Mouse Genome Database (MGD), Gene Expression Database (GXD), Mouse Models of Human Cancer database (MMHCdb) (formerly Mouse Tumor Biology (MTB)), Gene Ontology (GO)
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last database update
09/17/2024
MGI 6.24
The Jackson Laboratory