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Gene Expression Data
Assay Details
Assay
Reference: J:61488 Pennisi D, et al., Mutations in Sox18 underlie cardiovascular and hair follicle defects in ragged mice. Nat Genet. 2000 Apr;24(4):434-7
Assay type: RNA in situ
MGI Accession ID: MGI:7266262
Gene symbol: Sox18
Gene name: SRY (sex determining region Y)-box 18
Probe: Sox18 probe3
Probe preparation: Antisense labelled with digoxigenin RNA
Visualized with: Alkaline phosphatase
Results
Specimen 1a: embryonic day 7.5 (more )
Structure Level Pattern Image Note
TS11: allantois Present 1a
TS11: blood island Present 1a

Specimen 1b: embryonic day 8.0 (more )
Structure Level Pattern Image Note
TS12: allantois Present 1b
TS12: blood island Present 1b
TS12: endocardial tube Present 1b Expression in cells fated to become the endocardium.

Specimen 1c: embryonic day 8.5 (more )
Structure Level Pattern Image Note
TS13: allantois Present 1c
TS13: yolk sac blood vessel Present 1c
TS13: dorsal aorta Present 1c
TS13: heart Present 1c

Specimen 1d: embryonic day 8.5; Flt1tm1Jrt/Flt1tm1Jrt (more )
Structure Level Pattern Image Note
TS13: vascular system Present Regionally restricted 1d Expression in pattern reflecting disturbed blood vessel development

Specimen 1e: embryonic day 8.5; Kdrtm1Jrt/Kdrtm1Jrt (more )
Structure Level Pattern Image Note
TS13: embryo Absent 1e

Specimen 1g: embryonic day 9.5 (more )
Structure Level Pattern Image Note
TS15: intersomitic blood vessel Present 1g
TS15: head blood vessel Present 1g Expression in network of smaller vessels in head and trunk mesenchyme.
TS15: trunk blood vessel Present 1g Expression in network of smaller vessels in head and trunk mesenchyme.

Specimen 1h: embryonic day 11.0 (more )
Structure Level Pattern Image Note
TS18: intersomitic blood vessel Present 1h
TS18: trunk blood vessel Present Regionally restricted 1h Expression in branching network of smaller vessels formed by angiogenesis.

Specimen 1i: embryonic day 12.5 (more )
Structure Level Pattern Image Note
TS20: trunk blood vessel Present Regionally restricted 1i Expression in branching vessels on surface of abdomen.
TS20: intersomitic blood vessel Present 1i Expression in vessels between somites.
TS20: vibrissa follicle Strong 1i High levels of expression in nascent vibrissa follicles.

Specimen 1j: embryonic day 8.0 (more )
Structure Cell Type Level Pattern Image Note
TS12: yolk sac mesenchyme Present 1j
TS12: vascular system gut endothelial cell Present Regionally restricted 1j Expression in endothelial cells around foregut.
TS12: cardiogenic plate endocardial cell Present Regionally restricted 1j Expression in presumptive endocardial cells of cardiogenic plate.

Specimen 1k: embryonic day 9.5 (more )
Structure Cell Type Level Pattern Image Note
TS15: dorsal aorta aortic endothelial cell Present Regionally restricted 1k Expression in presumptive endocardial cells of cardiogenic plate.

Specimen 1l: embryonic day 9.5 (more )
Structure Cell Type Level Pattern Image Note
TS15: intersomitic blood vessel blood vessel endothelial cell Present Regionally restricted 1l Expression in endothelial cells of intersomitic vessels.
TS15: yolk sac mesenchyme endothelial cell Present 1l Expression in endothelial cells of yolk sac mesoderm.

Specimen 1m: embryonic day 9.5 (more )
Structure Cell Type Level Pattern Image Note
TS15: intersomitic blood vessel blood vessel endothelial cell Present 1m Expression in endothelial cells of intersomitic vessel.

Specimen 2a: embryonic day 14.0 (more )
Structure Level Pattern Image Note
TS22: vibrissa follicle Present 2a
TS22: hair follicle Present 2a Expression in first wave of pelage hair follicles.

Specimen not shown: embryonic day 15.0 (more )
Structure Level Pattern Image Note
TS23: vibrissa follicle Present Expression in vibrissae follicle persisted until E15.0.

Specimen 2b: embryonic day 14.0 (more )
Structure Level Pattern Image Note
TS22: vibrissa dermal component Present Regionally restricted 2b Expression in underlying mesenchyme adjacent to epithelial placode, persists in mesenchymal cells surrounding invaginating epithelium until dermal papillae stage.


Contributing Projects:
Mouse Genome Database (MGD), Gene Expression Database (GXD), Mouse Models of Human Cancer database (MMHCdb) (formerly Mouse Tumor Biology (MTB)), Gene Ontology (GO)
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last database update
09/17/2024
MGI 6.24
The Jackson Laboratory