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Gene Expression Data
Assay Details
Assay
Reference: J:316418 Azzoni E, et al., The onset of circulation triggers a metabolic switch required for endothelial to hematopoietic transition. Cell Rep. 2021 Dec 14;37(11):110103
Assay type: Immunohistochemistry
MGI Accession ID: MGI:7276246
Gene symbol: Jag1
Gene name: jagged 1
Antibody: anti-Jag1 (AF599)
Detection system: Secondary antibody
Results
Specimen 2F +/+ Jag1: embryonic day 9.5 (more )
Note: 23-25 somite pairs. Triple labeled: red - Jag1; white - VE-Cad (Cdh5 assay MGI:7276242); green - Runx1 (assay MGI:7276241).
Structure Level Pattern Image Note
TS15: dorsal aorta Present 2F Jag1 +/+ , 2F VE-Cad/Jag1/Runx1 +/+
Specimen 2F -/- Jag1: embryonic day 9.5; Slc8a1tm1Sjc/Slc8a1tm1Sjc (more )
Note: 23-25 somite pairs. Triple labeled: red - Jag1; white - VE-Cad (Cdh5 assay MGI:7276242); green - Runx1 (assay MGI:7276241).
Structure Level Pattern Image Note
TS15: dorsal aorta Absent 2F VE-Cad/Jag1/Runx1 -/- , 2F Jag1 -/- Authors report lack of expression in mutant embryos.
Contributing Projects:
Mouse Genome Database (MGD), Gene Expression Database (GXD), Mouse Models of Human Cancer database (MMHCdb) (formerly Mouse Tumor Biology (MTB)), Gene Ontology (GO)
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12/17/2024
MGI 6.24 		The Jackson Laboratory