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Gene Expression Data
Assay Details
Assay
Reference: J:323868 Bellchambers HM, et al., Loss of Zic3 impairs planar cell polarity leading to abnormal left-right signaling, heart defects and neural tube defects. Hum Mol Genet. 2021 Nov 30;30(24):2402-2415
Assay type: Immunohistochemistry
MGI Accession ID: MGI:7277844
Gene symbol: Tubg2
Gene name: tubulin, gamma 2
Antibody: anti-gamma-tubulin (T5192)
Detection system: Secondary antibody coupled to Alexa Fluor 594
Results
Specimen 1A WT: embryonic day 8.0 (more )
Note: 0-1 somite stage. Double labeled: red - Tubg1 and Tubg2; green - F-actin labeled with phalloidin.
Structure Level Pattern Image Note
TS12: node Present 1A WT (upper) , 1A WT (lower)
Specimen 1A Zic3 null: embryonic day 8.0; Zic3tm1Bca/Zic3tm1Bca (more )
Note: 0-1 somite stage. Double labeled: red - Tubg1 and Tubg2; green - F-actin labeled with phalloidin.
Structure Level Pattern Image Note
TS12: node Present Regionally restricted 1A Zic3 null (lower) , 1A Zic3 null (upper) Positioning of cilia altered in Zic3 null embryos.
Specimen S1A WT: embryonic day 8.0 (more )
Note: 0-1 somite stage. Double labeled: red - Tubg1 and Tubg2; green - F-actin labeled with phalloidin.
Structure Level Pattern Image Note
TS12: node Present S1A
Specimen S1 Zic3 null: embryonic day 8.0; Zic3tm1Bca/Zic3tm1Bca (more )
Note: 0-1 somite stage. Double labeled: red - Tubg1 and Tubg2; green - F-actin labeled with phalloidin.
Structure Level Pattern Image Note
TS12: node Present Regionally restricted S1B Node cells less elongated than in wild type.
Contributing Projects:
Mouse Genome Database (MGD), Gene Expression Database (GXD), Mouse Models of Human Cancer database (MMHCdb) (formerly Mouse Tumor Biology (MTB)), Gene Ontology (GO)
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03/25/2025
MGI 6.24 		The Jackson Laboratory