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Tubb3em1(icre)Imayo
Endonuclease-mediated Allele Detail
Summary
Symbol: Tubb3em1(icre)Imayo
Name: tubulin, beta 3 class III; endonuclease-mediated mutation 1, Itaru Imayoshi
MGI ID: MGI:7282232
Synonyms: Tubb3em1(icre)Inot, Tubb3-T2A-iCre
Gene: Tubb3  Location: Chr8:124138292-124148754 bp, + strand  Genetic Position: Chr8, 72.1 cM
Alliance: Tubb3em1(icre)Imayo page
Mutation
origin
Strain of Origin:  Not Specified
Mutation
description
Allele Type:    Endonuclease-mediated (Recombinase)
Mutation:    Insertion
 
Tubb3em1(icre)Imayo expression driven by 1 gene
 
Mutation details: Using CRISPR/cas9 technology, a T2A-iCre expression cassette was inserted into Tubb3 gene just upstream of the stop codon. (J:314171)
Recombinase
activity
Activity:
 Tissue activity of this recombinase allele
Driver: Tubb3 (mouse)
Summary of all recombinase alleles driven by Tubb3.
 

Find Mice (IMSR)
Mouse strains and cell lines available from the International Mouse Strain Resource (IMSR)
Carrying this Mutation:  Mouse Strains: 0 strains available      Cell Lines: 0 lines available
Carrying any Tubb3 Mutation:  30 strains or lines available
References
Original:  J:314171 Inoue YU, et al., An Optimized Preparation Method for Long ssDNA Donors to Facilitate Quick Knock-In Mouse Generation. 7 new recombinases (including the one already entered), and 5 different reporter alleles. Cells. 2021 Apr 30;10(5)
All:  1 reference(s)
Contributing Projects:
Mouse Genome Database (MGD), Gene Expression Database (GXD), Mouse Models of Human Cancer database (MMHCdb) (formerly Mouse Tumor Biology (MTB)), Gene Ontology (GO)
Citing These Resources
Funding Information
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Send questions and comments to User Support. 		last database update
08/02/2024
MGI 6.24 		The Jackson Laboratory