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Oxtrem4(icre/ERT2)Yinn
Endonuclease-mediated Allele Detail
Summary
Symbol: Oxtrem4(icre/ERT2)Yinn
Name: oxytocin receptor; endonuclease-mediated mutation 4, Yukiko U Inoue
MGI ID: MGI:7282236
Synonyms: Oxtr3xHA-iCreERT2, Oxtrem2(icre/ERT2)Inot, Oxtr-T2A-iCre-ERT2
Gene: Oxtr  Location: Chr6:112450644-112466904 bp, - strand  Genetic Position: Chr6, 52.27 cM, cytoband E3
Alliance: Oxtrem4(icre/ERT2)Yinn page
Mutation
origin
Strain of Origin:  (C57BL/6 x C3H)F1
Mutation
description
Allele Type:    Endonuclease-mediated (Epitope tag, Inducible, Recombinase)
Inducer:    tamoxifen
Mutation:    Insertion
 
Oxtrem4(icre/ERT2)Yinn expression driven by 1 gene
 
Mutation details: Using CRISPR/cas9 technology, three copies of HA-tag and a T2A-iCre-ERT2 expression cassette were inserted into the Oxtr gene just upstream of the stop codon. (J:314171)
Recombinase
activity
Activity:
 Tissue activity of this recombinase allele
Driver: Oxtr (mouse)
Summary of all recombinase alleles driven by Oxtr.
 

Expression
In Mice Carrying this Mutation: 13 assay results
Find Mice (IMSR)
Mouse strains and cell lines available from the International Mouse Strain Resource (IMSR)
Carrying this Mutation:  Mouse Strains: 1 strain available      Cell Lines: 0 lines available
Carrying any Oxtr Mutation:  41 strains or lines available
References
Original:  J:314171 Inoue YU, et al., An Optimized Preparation Method for Long ssDNA Donors to Facilitate Quick Knock-In Mouse Generation. 7 new recombinases (including the one already entered), and 5 different reporter alleles. Cells. 2021 Apr 30;10(5)
All:  2 reference(s)
Contributing Projects:
Mouse Genome Database (MGD), Gene Expression Database (GXD), Mouse Models of Human Cancer database (MMHCdb) (formerly Mouse Tumor Biology (MTB)), Gene Ontology (GO)
Citing These Resources
Funding Information
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Send questions and comments to User Support. 		last database update
11/12/2024
MGI 6.24 		The Jackson Laboratory