Ccdc38<em1Cya> Endonuclease-mediated Allele Detail MGI Mouse (MGI:7287391)

Ccdc38^em1Cya
Endonuclease-mediated Allele Detail

Summary

Symbol:	Ccdc38^em1Cya
Name:	coiled-coil domain containing 38; endonuclease-mediated mutation 1, Cyagen Biosciences
MGI ID:	MGI:7287391
Synonyms:	Ccdc38^-, Ccdc38^em1cyagen
Gene:	Ccdc38 Location: Chr10:93376494-93420189 bp, + strand Genetic Position: Chr10, 48.55 cM
Alliance:	Ccdc38^em1Cya page

Mutation
origin

Strain of Origin:

C57BL/6J

Mutation
description

Allele Type:		Endonuclease-mediated (Null/knockout)
Mutation:		Intragenic deletion
		Mutation details: CRISPR/Cas9 technology deleted exons 5-11. Western blot analysis confirmed the complete absence of encoded protein in total protein extracts from homozygous mutant testes. (J:325559)

Phenotypes

View phenotypes and curated references for all genotypes (concatenated display).

Expression

In Structures Affected by this Mutation:

Find Mice (IMSR)

Mouse strains and cell lines available from the International Mouse Strain Resource (IMSR)
Carrying this Mutation:	Mouse Strains: 1 strain available Cell Lines: 0 lines available
Carrying any Ccdc38 Mutation:	37 strains or lines available

References

Original:	J:325559 Zhang R, et al., CCDC38 is required for sperm flagellum biogenesis and male fertility in mice. Development. 2022 Jun 1;149(11):dev200516
All:	1 reference(s)

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