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Calb2em1(icre)Smoc
Endonuclease-mediated Allele Detail
Summary
Symbol: Calb2em1(icre)Smoc
Name: calbindin 2; endonuclease-mediated mutation 1, Shanghai Model Organisms Center
MGI ID: MGI:7288605
Synonyms: Calb2em1(IRES-iCre-SV40-pA)Smoc
Gene: Calb2  Location: Chr8:110869158-110894844 bp, - strand  Genetic Position: Chr8, 57.44 cM
Alliance: Calb2em1(icre)Smoc page
Mutation
origin
Strain of Origin:  C57BL/6J
Mutation
description
Allele Type:    Endonuclease-mediated (Recombinase)
Mutation:    Insertion
 
Calb2em1(icre)Smoc expression driven by 1 gene
 
Mutation details: A IRES-iCre expression cassette was knocked into the Calb2 gene stop codon site. Calb2 gene encodes calbindin 2. When crossed with a strain carrying a gene flanked by loxP sites, the flanked gene will be removed in cells expressing cre. The protein plays a key role in the nervous system. (J:238766)
Inheritance:    Not Specified
Recombinase
activity
Activity:
 Tissue activity of this recombinase allele
Driver: Calb2 (mouse)
Summary of all recombinase alleles driven by Calb2.
 

Find Mice (IMSR)
Mouse strains and cell lines available from the International Mouse Strain Resource (IMSR)
Carrying this Mutation:  Mouse Strains: 0 strains available      Cell Lines: 0 lines available
Carrying any Calb2 Mutation:  23 strains or lines available
References
Original:  J:238766 Shanghai Model Organisms Center, Information obtained from the Shanghai Model Organisms Center (SMOC), Shanghai, China. MGI Direct Data Submission. 2017;
All:  1 reference(s)
Contributing Projects:
Mouse Genome Database (MGD), Gene Expression Database (GXD), Mouse Models of Human Cancer database (MMHCdb) (formerly Mouse Tumor Biology (MTB)), Gene Ontology (GO)
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Send questions and comments to User Support. 		last database update
11/12/2024
MGI 6.24 		The Jackson Laboratory