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Il13em1(icre)Smoc
Endonuclease-mediated Allele Detail
Summary
Symbol: Il13em1(icre)Smoc
Name: interleukin 13; endonuclease-mediated mutation 1, Shanghai Model Organisms Center
MGI ID: MGI:7290424
Synonyms: Il13em1(IRES-iCre)Smoc
Gene: Il13  Location: Chr11:53522151-53525529 bp, - strand  Genetic Position: Chr11, 31.98 cM
Alliance: Il13em1(icre)Smoc page
Mutation
origin
Strain of Origin:  C57BL/6J
Mutation
description
Allele Type:    Endonuclease-mediated (Recombinase)
Mutation:    Insertion
 
Il13em1(icre)Smoc expression driven by 1 gene
 
Mutation detailsA IRES-iCre expression cassette was knocked into the Il13 gene stop codon site. This gene encodes a multifunctional cytokine. When crossed with a strain carrying a gene flanked by loxP sites, the flanked gene will be removed in cells expressing cre. This cytokine participates in the regulation of immune response, inflammatory response and hematopoietic process. (J:238766)
Inheritance:    Not Specified
Recombinase
activity
Activity:
 Tissue activity of this recombinase allele
Driver: Il13 (mouse)
Summary of all recombinase alleles driven by Il13.
 

Find Mice (IMSR)
Mouse strains and cell lines available from the International Mouse Strain Resource (IMSR)
Carrying this Mutation:  Mouse Strains: 0 strains available      Cell Lines: 0 lines available
Carrying any Il13 Mutation:  30 strains or lines available
References
Original:  J:238766 Shanghai Model Organisms Center, Information obtained from the Shanghai Model Organisms Center (SMOC), Shanghai, China. MGI Direct Data Submission. 2017;
All:  1 reference(s)

Contributing Projects:
Mouse Genome Database (MGD), Gene Expression Database (GXD), Mouse Models of Human Cancer database (MMHCdb) (formerly Mouse Tumor Biology (MTB)), Gene Ontology (GO)
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last database update
11/12/2024
MGI 6.24
The Jackson Laboratory