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Adipoqem1(cre)Oam
Endonuclease-mediated Allele Detail
Summary
Symbol: Adipoqem1(cre)Oam
Name: adiponectin, C1Q and collagen domain containing; endonuclease-mediated mutation 1, Ormond A MacDougald
MGI ID: MGI:7294222
Synonyms: Adipoq-Cre
Gene: Adipoq  Location: Chr16:22965286-22976718 bp, + strand  Genetic Position: Chr16, 13.96 cM, cytoband B3-B4
Alliance: Adipoqem1(cre)Oam page
Mutation
origin
Strain of Origin:  C57BL/6 x SJL
Mutation
description
Allele Type:    Endonuclease-mediated (Conditional ready, Recombinase)
Mutation:    Insertion
 
Adipoqem1(cre)Oam expression driven by 1 gene
 
Mutation details: CRISPR/cas9 endonuclease-mediated genome editing was used to insert an in frame protein containing IRES-followed by F3-FRT-Cre-F3-FRT in reverse orientation into the 3' UTR of the gene. The cassette contained approximately 1 kb of 5' and 5' flanking homology arm sequence. Expression of Flpo recombinase recombines cre to the correct orientation. (J:325967)
Recombinase
activity
Activity:
 Tissue activity of this recombinase allele
Driver: Adipoq (mouse)
Summary of all recombinase alleles driven by Adipoq.
 

Find Mice (IMSR)
Mouse strains and cell lines available from the International Mouse Strain Resource (IMSR)
Carrying this Mutation:  Mouse Strains: 1 strain available      Cell Lines: 0 lines available
Carrying any Adipoq Mutation:  40 strains or lines available
References
Original:  J:325967 Li Z, et al., Lipolysis of bone marrow adipocytes is required to fuel bone and the marrow niche during energy deficits. Elife. 2022 Jun 22;11:e78496
All:  4 reference(s)
Contributing Projects:
Mouse Genome Database (MGD), Gene Expression Database (GXD), Mouse Models of Human Cancer database (MMHCdb) (formerly Mouse Tumor Biology (MTB)), Gene Ontology (GO)
Citing These Resources
Funding Information
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Send questions and comments to User Support. 		last database update
11/19/2024
MGI 6.24 		The Jackson Laboratory