About   Help   FAQ
Adipoqem1(cre)Oam
Endonuclease-mediated Allele Detail
Summary
Symbol: Adipoqem1(cre)Oam
Name: adiponectin, C1Q and collagen domain containing; endonuclease-mediated mutation 1, Ormond A MacDougald
MGI ID: MGI:7294222
Synonyms: Adipoq-Cre
Gene: Adipoq  Location: Chr16:22965286-22976718 bp, + strand  Genetic Position: Chr16, 13.96 cM, cytoband B3-B4
Alliance: Adipoqem1(cre)Oam page
Mutation
origin
Strain of Origin:  C57BL/6 x SJL
Mutation
description
Allele Type:    Endonuclease-mediated (Conditional ready, Recombinase)
Mutation:    Insertion
 
Adipoqem1(cre)Oam expression driven by 1 gene
 
Mutation details: CRISPR/cas9 endonuclease-mediated genome editing was used to insert an in frame protein containing IRES-followed by F3-FRT-Cre-F3-FRT in reverse orientation into the 3' UTR of the gene. The cassette contained approximately 1 kb of 5' and 5' flanking homology arm sequence. Expression of Flpo recombinase recombines cre to the correct orientation. (J:325967)
Recombinase
activity
Activity:
 Tissue activity of this recombinase allele
Driver: Adipoq (mouse)
Summary of all recombinase alleles driven by Adipoq.
 

Find Mice (IMSR)
Mouse strains and cell lines available from the International Mouse Strain Resource (IMSR)
Carrying this Mutation:  Mouse Strains: 1 strain available      Cell Lines: 0 lines available
Carrying any Adipoq Mutation:  39 strains or lines available
References
Original:  J:325967 Li Z, et al., Lipolysis of bone marrow adipocytes is required to fuel bone and the marrow niche during energy deficits. Elife. 2022 Jun 22;11:e78496
All:  4 reference(s)
Contributing Projects:
Mouse Genome Database (MGD), Gene Expression Database (GXD), Mouse Models of Human Cancer database (MMHCdb) (formerly Mouse Tumor Biology (MTB)), Gene Ontology (GO)
Citing These Resources
Funding Information
Warranty Disclaimer, Privacy Notice, Licensing, & Copyright
Send questions and comments to User Support. 		last database update
07/02/2024
MGI 6.13 		The Jackson Laboratory