Lgr5<em1(cre/ERT2)Gpt> Endonuclease-mediated Allele Detail MGI Mouse (MGI:7301624)

Lgr5^{em1(cre/ERT2)Gpt}
Endonuclease-mediated Allele Detail

Summary

Symbol:	Lgr5^{em1(cre/ERT2)Gpt}
Name:	leucine rich repeat containing G protein coupled receptor 5; endonuclease-mediated mutation 1, GemPharmatech Co., Ltd
MGI ID:	MGI:7301624
Synonyms:	Lgr5^em1-cre/ERT2
Gene:	Lgr5 Location: Chr10:115286219-115423685 bp, - strand Genetic Position: Chr10, 63.51 cM
Alliance:	Lgr5^{em1(cre/ERT2)Gpt} page

Mutation
origin

Strain of Origin:

C57BL/6JGpt

Mutation
description

Allele Type:

Endonuclease-mediated (Inducible, Recombinase)

Inducer:

tamoxifen

Mutation:

Insertion

Lgr5^{em1(cre/ERT2)Gpt} expression driven by 1 gene

CRISPR-targeting introduced an inducible recombinase gene fusion (cre/ERT2). (J:293217)

Inheritance:

Not Specified

Recombinase
activity

Activity:	Tissue activity of this recombinase allele
Driver:	Lgr5 (mouse) Summary of all recombinase alleles driven by Lgr5. Alliance mouse Lgr5 gene page

Find Mice (IMSR)

Mouse strains and cell lines available from the International Mouse Strain Resource (IMSR)
Carrying this Mutation:	Mouse Strains: 0 strains available Cell Lines: 0 lines available
Carrying any Lgr5 Mutation:	58 strains or lines available

References

Original:	J:293217 GemPharmatech, GemPharmatech Website. 2020;
All:	3 reference(s)

Contributing Projects: Mouse Genome Database (MGD), Gene Expression Database (GXD), Mouse Models of Human Cancer database (MMHCdb) (formerly Mouse Tumor Biology (MTB)), Gene Ontology (GO)
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