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Gene Expression Data
Assay Details
Assay
Reference: J:243375 Choi D, et al., Laminar flow downregulates Notch activity to promote lymphatic sprouting. J Clin Invest. 2017 Apr 03;127(4):1225-1240
Assay type: Immunohistochemistry
MGI Accession ID: MGI:7310039
Gene symbol: Pecam1
Gene name: platelet/endothelial cell adhesion molecule 1
Antibody: MEC 13.3
Results
Specimen 3A WT: embryonic day 15.5 (more )
Structure Level Pattern Image Note
TS23: back skin Present 3A WT Blood vessel , 3A WT Blood vessel enlarged
TS23: blood vessel Present 3A WT Blood vessel , 3A WT Blood vessel enlarged

Specimen 3A KO: embryonic day 15.5; Orai1tm1Rao/Orai1tm1Rao (more )
Structure Level Pattern Image Note
TS23: back skin Present 3A KO Blood vessel , 3A KO Blood vessel enlarged This mutant has slightly denser vascular networks with increased number of branching points and marginally reduced distance between the branching points compared to wild-type.
TS23: blood vessel Present 3A KO Blood vessel , 3A KO Blood vessel enlarged This mutant has slightly denser vascular networks with increased number of branching points and marginally reduced distance between the branching points compared to wild-type.

Specimen 3B WT: embryonic day 15.5 (more )
Structure Level Pattern Image Note
TS23: blood vessel Present 3B WT Blood vessel enlarged , 3B WT Blood vessel
TS23: ear Present 3B WT Blood vessel enlarged , 3B WT Blood vessel

Specimen 3B KO: embryonic day 15.5; Orai1tm1Rao/Orai1tm1Rao (more )
Structure Level Pattern Image Note
TS23: blood vessel Present 3B KO Blood vessel , 3B KO Blood vessel enlarged This mutant has slightly denser vascular networks with increased number of branching points and marginally reduced distance between the branching points compared to wild-type.
TS23: ear Present 3B KO Blood vessel , 3B KO Blood vessel enlarged This mutant has slightly denser vascular networks with increased number of branching points and marginally reduced distance between the branching points compared to wild-type.

Specimen 6I WT: embryonic day 15.5 (more )
Structure Level Pattern Image Note
TS23: back skin Present 6I WT CD31 left , 6I WT CD31 right
TS23: blood vessel Present 6I WT CD31 left , 6I WT CD31 right

Specimen 6I KO: embryonic day 15.5; Dtx3lem1Ykho/Dtx3lem1Ykho (more )
Structure Level Pattern Image Note
TS23: back skin Present 6I KO CD31 left , 6I KO CD31 right
TS23: blood vessel Present 6I KO CD31 left , 6I KO CD31 right

Specimen S3 A: embryonic day 15.5 (more )
Structure Level Pattern Image Note
TS23: back skin Present S3A
TS23: blood vessel Present S3A

Specimen S3 B: embryonic day 15.5 (more )
Structure Level Pattern Image Note
TS23: back skin Present S3B
TS23: blood vessel Present S3B

Specimen S3 E: embryonic day 15.5; Orai1tm1Rao/Orai1tm1Rao (more )
Structure Level Pattern Image Note
TS23: back skin Present S3E This mutant has slightly denser vascular networks with increased number of branching points and marginally reduced distance between the branching points compared to wild-type.
TS23: blood vessel Present S3E This mutant has slightly denser vascular networks with increased number of branching points and marginally reduced distance between the branching points compared to wild-type.

Specimen S3 F: embryonic day 15.5; Orai1tm1Rao/Orai1tm1Rao (more )
Structure Level Pattern Image Note
TS23: back skin Present S3F This mutant has slightly denser vascular networks with increased number of branching points and marginally reduced distance between the branching points compared to wild-type.
TS23: blood vessel Present S3F This mutant has slightly denser vascular networks with increased number of branching points and marginally reduced distance between the branching points compared to wild-type.


Contributing Projects:
Mouse Genome Database (MGD), Gene Expression Database (GXD), Mouse Models of Human Cancer database (MMHCdb) (formerly Mouse Tumor Biology (MTB)), Gene Ontology (GO)
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last database update
09/17/2024
MGI 6.24
The Jackson Laboratory