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Tg(NKX2-5*-cre)#Kyuhl
Transgene Detail
Summary
Symbol: Tg(NKX2-5*-cre)#Kyuhl
Name: transgene insertion, Kyu-Ho Lee
MGI ID: MGI:7314947
Synonyms: CNkx2.5-SHFnm-cre
Transgene: Tg(NKX2-5*-cre)#Kyuhl  Location: unknown  Genetic Position: ChrUN, Syntenic
Alliance: Tg(NKX2-5*-cre)#Kyuhl page
Transgene
origin
Strain of Origin:  FVB
Transgene
description
Transgene Type:    Transgenic (Recombinase)
Mutation:    Insertion
 
Tg(NKX2-5*-cre)#Kyuhl expression driven by 1 gene
 
Mutation detailsA mutated version of the chicken second heart field (SHF) NK2 homeobox 5 enhancer (cardiac activating region 3 (CAR3); nucleotides 976-3047 after transcriptional start site), where the Nkx2-5-binding consensus sequence in the BMP response element (BMPRE) was mutated from TCTGAGTG to TCTGCGAG, was used to drive the expression of the cre recombinase gene. Founder information and line numbers were not available. The pound symbol (#) is used when no line is specified and/or lines are pooled. (J:192448)
Recombinase
activity
Activity:
 Tissue activity of this recombinase allele
Driver: NKX2-5 (chicken)
Summary of all recombinase alleles driven by NKX2-5.
 

Find Mice (IMSR)
Mouse strains and cell lines available from the International Mouse Strain Resource (IMSR)
Carrying this Mutation:  Mouse Strains: 0 strains available      Cell Lines: 0 lines available
References
Original:  J:192448 Clark CD, et al., Evolutionary conservation of Nkx2.5 autoregulation in the second heart field. Dev Biol. 2013 Feb 1;374(1):198-209
All:  1 reference(s)

Contributing Projects:
Mouse Genome Database (MGD), Gene Expression Database (GXD), Mouse Models of Human Cancer database (MMHCdb) (formerly Mouse Tumor Biology (MTB)), Gene Ontology (GO)
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last database update
11/19/2024
MGI 6.24
The Jackson Laboratory