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Gene Expression Data
Assay Details
Assay
Reference: J:173286 Long JE, et al., Dlx1&2 and Mash1 transcription factors control MGE and CGE patterning and differentiation through parallel and overlapping pathways. Cereb Cortex. 2009 Jul;19 Suppl 1:i96-106
Assay type: RNA in situ
MGI Accession ID: MGI:7316456
Gene symbol: Isl1
Gene name: ISL1 transcription factor, LIM/homeodomain
Probe: Isl1 probe44
Probe preparation: Antisense labelled with digoxigenin RNA
Results
Specimen 2GG: embryonic day 15.5 (more )
Note: The genetic background of the control specimen was either wild type or heterozygous.
Structure Level Pattern Image Note
TS23: lateral ganglionic eminence Present 2GG
TS23: medial ganglionic eminence Weak 2GG
Specimen 2GG': embryonic day 15.5; Del(2Dlx1-Dlx2)1Jlr/Del(2Dlx1-Dlx2)1Jlr (more )
Structure Level Pattern Image Note
TS23: lateral ganglionic eminence Present 2GG' Expression is increased in this mutant compared to controls.
TS23: medial ganglionic eminence Present 2GG' There is ectopic and increased expression in this mutant compared to controls.
Specimen 2HH: embryonic day 15.5 (more )
Note: The genetic background of the control specimen was either wild type or heterozygous.
Structure Level Pattern Image Note
TS23: caudal ganglionic eminence Present 2HH
Specimen 2HH': embryonic day 15.5; Del(2Dlx1-Dlx2)1Jlr/Del(2Dlx1-Dlx2)1Jlr (more )
Structure Level Pattern Image Note
TS23: caudal ganglionic eminence Present Regionally restricted 2HH' Expression is increased in the ventricular zone in this mutant compared to controls.
Specimen S3I: embryonic day 15.5 (more )
Structure Level Pattern Image Note
TS23: lateral ganglionic eminence Present S3I
TS23: medial ganglionic eminence Present S3I
Specimen S3I': embryonic day 15.5; Del(2Dlx1-Dlx2)1Jlr/Del(2Dlx1-Dlx2)1Jlr (more )
Structure Level Pattern Image Note
TS23: lateral ganglionic eminence Present S3I'
TS23: medial ganglionic eminence Present S3I' There is ectopic expression in this mutant compared to controls.
Specimen S3I'': embryonic day 15.5; Ascl1tm1And/Ascl1tm1And (more )
Structure Level Pattern Image Note
TS23: medial ganglionic eminence Present S3I'' There is no major change in expression in this mutant compared to controls.
Specimen S3I''': embryonic day 15.5; Ascl1tm1And/Ascl1tm1And, Del(2Dlx1-Dlx2)1Jlr/Del(2Dlx1-Dlx2)1Jlr (more )
Structure Level Pattern Image Note
TS23: medial ganglionic eminence Present S3I''' There is ectopic expression in this mutant compared to controls.
Specimen S3J: embryonic day 15.5 (more )
Structure Level Pattern Image Note
TS23: caudal ganglionic eminence Present S3J
Specimen S3J': embryonic day 15.5; Del(2Dlx1-Dlx2)1Jlr/Del(2Dlx1-Dlx2)1Jlr (more )
Structure Level Pattern Image Note
TS23: caudal ganglionic eminence Present Regionally restricted S3J' Expression is increased in the ventricular zone in this mutant compared to controls.
Specimen S3J'': embryonic day 15.5; Ascl1tm1And/Ascl1tm1And (more )
Structure Level Pattern Image Note
TS23: caudal ganglionic eminence Present S3J'' There is no major change in expression in this mutant compared to controls.
Specimen S3J''': embryonic day 15.5; Ascl1tm1And/Ascl1tm1And, Del(2Dlx1-Dlx2)1Jlr/Del(2Dlx1-Dlx2)1Jlr (more )
Structure Level Pattern Image Note
TS23: caudal ganglionic eminence Present S3J''' Expression is increased in the ventricular zone in this mutant compared to controls.
Contributing Projects:
Mouse Genome Database (MGD), Gene Expression Database (GXD), Mouse Models of Human Cancer database (MMHCdb) (formerly Mouse Tumor Biology (MTB)), Gene Ontology (GO)
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06/12/2024
MGI 6.13 		The Jackson Laboratory