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Gene Expression Data
Assay Details
Assay
Reference: J:326587 Hurley S, et al., Distinct, dosage-sensitive requirements for the autism-associated factor CHD8 during cortical development. Mol Autism. 2021 Feb 24;12(1):16
Assay type: RT-PCR
MGI Accession ID: MGI:7316745
Gene symbol: Chd8
Gene name: chromodomain helicase DNA binding protein 8
Probe: Chd8-pC, Chd8-pD
Probe preparation: labelled with SYBR green
Assay notes: Quantitative RT-PCR. Relative expression was normalized to Gapdh and Ywhaz.
Results
Image: 1b ©

 Sample Information Bands Other Sample Information
Lane AgeStructure Size Not Specified Amount Genetic BackgroundMutant Allele(s)Sex
+/+ E9.5-10.5 TS16: telencephalon Present Not Specified involves: C57BL/6J Not Specified
+/- E9.5-10.5 TS16: telencephalon Weak (a) Not Specified involves: C57BL/6J Chd8tm1.2Mabn/Chd8+Not Specified
neo/neo E9.5-10.5 TS16: telencephalon Trace (b) Not Specified involves: C57BL/6J Chd8tm1Mabn/Chd8tm1MabnNot Specified
neo/- E9.5-10.5 TS16: telencephalon Trace (c) Not Specified involves: C57BL/6J Chd8tm1Mabn/Chd8tm1.2MabnNot Specified
Notes:
(a) Expression reduced 63% compared to wild type.
(b) Expression reduced 85% compared to wild type.
(c) Expression reduced 88% compared to wild type.
Contributing Projects:
Mouse Genome Database (MGD), Gene Expression Database (GXD), Mouse Models of Human Cancer database (MMHCdb) (formerly Mouse Tumor Biology (MTB)), Gene Ontology (GO)
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12/10/2024
MGI 6.24 		The Jackson Laboratory