Gt(ROSA)26Sortm11(flpo)Amc
Targeted Allele Detail
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Symbol: |
Gt(ROSA)26Sortm11(flpo)Amc |
Name: |
gene trap ROSA 26, Philippe Soriano; targeted mutation 11, Andrew P McMahon |
MGI ID: |
MGI:7327519 |
Synonyms: |
Rosa26 (FLPo) |
Gene: |
Gt(ROSA)26Sor Location: Chr6:113044389-113054205 bp, - strand Genetic Position: Chr6, 52.73 cM
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Alliance: |
Gt(ROSA)26Sortm11(flpo)Amc page
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Allele Type: |
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Targeted (Conditional ready, RMCE-ready, Recombinase) |
Mutation: |
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Insertion
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Gt(ROSA)26Sortm11(flpo)Amc expression driven by
1 gene
Knock-in expression driven by:
Organism |
Driver Gene |
Note |
Not Specified |
PGK1 |
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Mutation details: The following elements were inserted into the locus to create an RMCE (recombinase-mediated cassette exchange)-ready allele: a splice acceptor site, an ATG translation start site, an F3 site, a puromycin resistance gene cassette, a flpo recombinase gene cassette (with PGK promoter and poly(A) signal sequence), an FRT site and chicken beta-globin locus insulator sequence. When cells containing this allele are presented with a compatible RMCE vector, the sequence between the F3-FRT sites will be replaced with the sequence between the F3-FRT sites in the vector.
(J:327127)
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Activity: |
Tissue activity of this recombinase allele
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Driver:
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PGK1
(species not specified)
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Mouse strains and cell lines
available from the International Mouse Strain Resource
(IMSR) |
Carrying this Mutation: |
Mouse Strains: 0 strains available
Cell Lines: 0 lines available
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Carrying any Gt(ROSA)26Sor Mutation: |
994 strains or lines available
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Original: |
J:327127 Tsanov KM, et al., An embryonic stem cell-based system for rapid analysis of transcriptional enhancers. Genesis. 2012 May;50(5):443-50 |
All: |
1 reference(s) |
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