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Slco2a1em1(cre)Ngai
Endonuclease-mediated Allele Detail
Summary
Symbol: Slco2a1em1(cre)Ngai
Name: solute carrier organic anion transporter family, member 2a1; endonuclease-mediated mutation 1, John Ngai
MGI ID: MGI:7334983
Synonyms: Slco2a1-P2A-Cre
Gene: Slco2a1  Location: Chr9:102885686-102973201 bp, + strand  Genetic Position: Chr9, 54.72 cM
Alliance: Slco2a1em1(cre)Ngai page
Mutation
origin
Germline Transmission:  Earliest citation of germline transmission: J:325783
Parent Cell Line:  v6.5 (ES Cell)
Strain of Origin:  (C57BL/6 x 129S4/SvJae)F1
Mutation
description
Allele Type:    Endonuclease-mediated (Epitope tag, Recombinase)
Mutation:    Insertion
 
Slco2a1em1(cre)Ngai expression driven by 1 gene
 
Mutation detailsUsing CRISPR/Cas9 technology, a P2A-Cre and a Myc-tag were inserted after the STOP codon of the solute carrier organic anion transporter family member 2a1 gene (Slco2a1). (J:325783)
Recombinase
activity
Activity:
 Tissue activity of this recombinase allele
Driver: Slco2a1 (mouse)
Summary of all recombinase alleles driven by Slco2a1.
 

Find Mice (IMSR)
Mouse strains and cell lines available from the International Mouse Strain Resource (IMSR)
Carrying this Mutation:  Mouse Strains: 1 strain available      Cell Lines: 0 lines available
Carrying any Slco2a1 Mutation:  36 strains or lines available
References
Original:  J:325783 A multimodal cell census and atlas of the mammalian primary motor cortex. Nature. 2021 Oct;598(7879):86-102
All:  1 reference(s)

Contributing Projects:
Mouse Genome Database (MGD), Gene Expression Database (GXD), Mouse Models of Human Cancer database (MMHCdb) (formerly Mouse Tumor Biology (MTB)), Gene Ontology (GO)
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last database update
07/02/2024
MGI 6.13
The Jackson Laboratory