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Clec9atm4.1(cre/ERT2)Crs
Targeted Allele Detail
Summary
Symbol: Clec9atm4.1(cre/ERT2)Crs
Name: C-type lectin domain family 9, member a; targeted mutation 4.1, Caetano Reis e Sousa
MGI ID: MGI:7338965
Synonyms: Clec9aCreERT2
Gene: Clec9a  Location: Chr6:129385825-129401726 bp, + strand  Genetic Position: Chr6, 63.3 cM
Alliance: Clec9atm4.1(cre/ERT2)Crs page
Mutation
origin
Germline Transmission:  Earliest citation of germline transmission: J:327971
Parent Cell Line:  Bruce 4 (ES Cell)
Strain of Origin:  B6.Cg-Thy1a
Mutation
description
Allele Type:    Targeted (Inducible, Recombinase)
Mutation:    Insertion
 
Clec9atm4.1(cre/ERT2)Crs expression driven by 1 gene
 
Mutation details: The allele was generated by conventional gene targeting (knock-in) adding P2A CreERT2 to the Clec9a gene. An FRT-flanked Neo cassette in the original constructs was removed by crossing to an FLPe expressing strain. (J:327971)
Recombinase
activity
Activity:
 Tissue activity of this recombinase allele
Driver: Clec9a (mouse)
Summary of all recombinase alleles driven by Clec9a.
 

Find Mice (IMSR)
Mouse strains and cell lines available from the International Mouse Strain Resource (IMSR)
Carrying this Mutation:  Mouse Strains: 1 strain available      Cell Lines: 0 lines available
Carrying any Clec9a Mutation:  29 strains or lines available
References
Original:  J:327971 Frederico B, et al., DNGR-1-tracing marks an ependymal cell subset with damage-responsive neural stem cell potential. Dev Cell. 2022 Aug 22;57(16):1957-1975.e9
All:  1 reference(s)
Contributing Projects:
Mouse Genome Database (MGD), Gene Expression Database (GXD), Mouse Models of Human Cancer database (MMHCdb) (formerly Mouse Tumor Biology (MTB)), Gene Ontology (GO)
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Funding Information
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11/12/2024
MGI 6.24 		The Jackson Laboratory