Dmrt2 Immunohistochemistry Gene Expression Assay

Gene Expression Data
Assay Details

Assay

Reference:	J:306318 Ono K, et al., Dmrt2 promotes transition of endochondral bone formation by linking Sox9 and Runx2. Commun Biol. 2021 Mar 11;4(1):326
Assay type:	Immunohistochemistry
MGI Accession ID:	MGI:7339220
Gene symbol:	Dmrt2
Gene name:	doublesex and mab-3 related transcription factor 2

Antibody:	anti-Dmrt2 (ARP32224-P050)
Detection system:	Secondary antibody coupled to Alexa Fluor 555

Results

2c Dmrt2 ©

Specimen 2C: embryonic day 15.5 (more

)

Structure	Cell Type	Level	Image	Note
TS23: epiphyseal plate	growth plate cartilage chondrocyte	Strong	2c Dmrt2	Highly expressed in pre-hypertrophic chondrocytes.
TS23: epiphyseal plate hypertrophic zone	hypertrophic chondrocyte	Weak	2c Dmrt2
TS23: epiphyseal plate proliferative zone	growth plate cartilage chondrocyte	Weak	2c Dmrt2

S4b ©

Specimen S4b: postnatal week 2 (more

)

Structure	Level	Pattern	Image	Note
TS28: long bone epiphysis	Present	Regionally restricted	S4b	Expressed in pre-hypertrophic chondrocytes around the secondary ossification center.

S4d ©

Specimen S4d: postnatal week 4 (more

)

Structure	Level	Pattern	Image	Note
TS28: epiphyseal plate	Weak		S4d	Expression level was low in the growth plate.

S5b Dmrt2 ©

S5b Merge ©

Specimen S5b: embryonic day 15.5 (more

)
Note: Double labeled: red - Dmrt2; green - Sox9 (assay MGI:7339226).

Structure	Cell Type	Level	Pattern	Image	Note
TS23: epiphyseal plate	growth plate cartilage chondrocyte	Present		S5b Merge , S5b Dmrt2	Coexpressed with Sox9.

Contributing Projects: Mouse Genome Database (MGD), Gene Expression Database (GXD), Mouse Models of Human Cancer database (MMHCdb) (formerly Mouse Tumor Biology (MTB)), Gene Ontology (GO)
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