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Cryaaem1(cre/ERT2)Xfan
Endonuclease-mediated Allele Detail
Summary
Symbol: Cryaaem1(cre/ERT2)Xfan
Name: crystallin, alpha A; endonuclease-mediated mutation 1, Xingjun Fan
MGI ID: MGI:7345512
Synonyms: Cryaa(2A-Cre-ERT2), Cryaatm1(cre/ERT2)Xfan
Gene: Cryaa  Location: Chr17:31896905-31900704 bp, + strand  Genetic Position: Chr17, 17.09 cM, cytoband A3-B
Alliance: Cryaaem1(cre/ERT2)Xfan page
Mutation
origin
Strain of Origin:  C57BL/6J
Mutation
description
Allele Type:    Endonuclease-mediated (Inducible, Recombinase)
Inducer:    tamoxifen
Mutation:    Insertion
 
Cryaaem1(cre/ERT2)Xfan expression driven by 1 gene
 
Mutation details: CRISPR/cas9 mediated recombination using guide RNAs inserted a P2A-CreERT2 cassette creating an in frame fusion to the C-terminal portion of the gene. (J:101977, J:348650)
Recombinase
activity
Activity:
 Tissue activity of this recombinase allele
Driver: Cryaa (mouse)
Summary of all recombinase alleles driven by Cryaa.
 

Find Mice (IMSR)
Mouse strains and cell lines available from the International Mouse Strain Resource (IMSR)
Carrying this Mutation:  Mouse Strains: 0 strains available      Cell Lines: 0 lines available
Carrying any Cryaa Mutation:  15 strains or lines available
References
Original:  J:348650 Wei Z, et al., A tamoxifen-inducible Cre knock-in mouse for lens-specific gene manipulation. Exp Eye Res. 2022 Nov 11;226:109306
All:  2 reference(s)
Contributing Projects:
Mouse Genome Database (MGD), Gene Expression Database (GXD), Mouse Models of Human Cancer database (MMHCdb) (formerly Mouse Tumor Biology (MTB)), Gene Ontology (GO)
Citing These Resources
Funding Information
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Send questions and comments to User Support. 		last database update
10/09/2024
MGI 6.24 		The Jackson Laboratory