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Gene Expression Data
Assay Details
Assay
Reference: J:123566 Le TN, et al., Dlx homeobox genes promote cortical interneuron migration from the basal forebrain by direct repression of the semaphorin receptor neuropilin-2. J Biol Chem. 2007 Jun 29;282(26):19071-81
Assay type: RNA in situ
MGI Accession ID: MGI:7345822
Gene symbol: Nrp2
Gene name: neuropilin 2
Probe: Nrp2 probe1
Probe preparation: Antisense labelled with digoxigenin RNA
Results
Specimen 6a: embryonic day 16.5 (more )
Structure Level Pattern Image Note
TS24: forebrain Ambiguous 6a
Specimen 6b: embryonic day 16.5; Del(2Dlx1-Dlx2)1Jlr/Del(2Dlx1-Dlx2)1Jlr (more )
Structure Cell Type Level Pattern Image Note
TS24: lateral ganglionic eminence Present Regionally restricted 6b Progressive accumulation of expression was detected in the subventricular zone.
TS24: medial ganglionic eminence Present Regionally restricted 6b Progressive accumulation of expression was detected in the subventricular zone.
TS24: forebrain interneuron Present Regionally restricted 6b Small collections of interneurons with ectopic expression were observed in the mutant.
Specimen 6c: embryonic day 18.5 (more )
Structure Level Pattern Image Note
TS26: forebrain Ambiguous 6c
Specimen 6d: embryonic day 18.5; Del(2Dlx1-Dlx2)1Jlr/Del(2Dlx1-Dlx2)1Jlr (more )
Structure Cell Type Level Pattern Image Note
TS26: lateral ganglionic eminence Present Regionally restricted 6d Progressive accumulation of expression was detected in the subventricular zone.
TS26: medial ganglionic eminence Present Regionally restricted 6d Progressive accumulation of expression was detected in the subventricular zone.
TS26: forebrain interneuron Present Regionally restricted 6d Small collections of interneurons with ectopic expression were observed in the mutant.
Specimen S5Ab: embryonic day 13.5 (more )
Note: Double labeled: blue - Nrp2; brown - Dlx1 (assay MGI:7345819).
Structure Level Pattern Image Note
TS21: telencephalon mantle layer Present s5Ac , s5Ab
Specimen S5Ae: embryonic day 13.5 (more )
Note: Double labeled: blue - Nrp2; brown - Dlx2 (assay MGI:7345821).
Structure Level Pattern Image Note
TS21: telencephalon mantle layer Present s5Ae , s5Af
Specimen S5Ag: embryonic day 13.5 (more )
Note: Double labeled: blue - Nrp2; brown - Dlx1 (assay MGI:7345819).
Structure Level Pattern Image Note
TS21: telencephalon Present s5Ag The majority of Dlx1-positive cells did not co-express Nrp2.
Specimen S5Ah: embryonic day 13.5 (more )
Note: Double labeled: blue - Nrp2; brown - Dlx2 (assay MGI:7345821).
Structure Level Pattern Image Note
TS21: telencephalon Present s5Ah The majority of Dlx2-positive cells did not co-express Nrp2.
Specimen S5Bb: embryonic day 16.5 (more )
Note: Double labeled: blue - Nrp2; brown - Dlx1 (assay MGI:7345819).
Structure Level Pattern Image Note
TS24: telencephalon mantle layer Present s5Bb , s5Bc
Specimen S5Be: embryonic day 16.5 (more )
Note: Double labeled: blue - Nrp2; brown - Dlx2 (assay MGI:7345821).
Structure Level Pattern Image Note
TS24: telencephalon mantle layer Present s5Bf , s5Be
Specimen S5Bg: embryonic day 16.5 (more )
Note: Double labeled: blue - Nrp2; brown - Dlx1 (assay MGI:7345819).
Structure Level Pattern Image Note
TS24: telencephalon Present s5Bg The majority of Dlx1-positive cells did not co-express Nrp2.
Specimen S5Bh: embryonic day 16.5 (more )
Note: Double labeled: blue - Nrp2; brown - Dlx2 (assay MGI:7345821).
Structure Level Pattern Image Note
TS24: telencephalon Present s5Bh The majority of Dlx2-positive cells did not co-express Nrp2.
Contributing Projects:
Mouse Genome Database (MGD), Gene Expression Database (GXD), Mouse Models of Human Cancer database (MMHCdb) (formerly Mouse Tumor Biology (MTB)), Gene Ontology (GO)
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09/17/2024
MGI 6.24 		The Jackson Laboratory