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Gene Expression Data
Assay Details
Assay
Reference: J:283039 Giralt A, et al., Helios modulates the maturation of a CA1 neuronal subpopulation required for spatial memory formation. Exp Neurol. 2020 Jan;323:113095
Assay type: Immunohistochemistry
MGI Accession ID: MGI:7367517
Gene symbol: Ikzf2
Gene name: IKAROS family zinc finger 2
Antibody: anti-Helios (sc-9864)
Assay notes: Data presented in Supplementary Table 1.
Results
Specimen E14.5 not shown: embryonic day 14.5 (more )
Structure Level Pattern Image Note
TS22: corpus striatum Trace Authors report very few expressing cells.
TS22: lateral ganglionic eminence Trace Authors report very few expressing cells.
TS22: hippocampus Absent No expression in pyramidal layer of hippocampal CA1.
TS22: cerebellum Absent No expression in Purkinje cell layer of cerebellum.

Specimen E16.5 not shown: embryonic day 16.5 (more )
Structure Level Pattern Image Note
TS24: corpus striatum Present Authors report several expressing cells.
TS24: lateral ganglionic eminence Present Authors report several expressing cells.
TS24: hippocampus Weak Regionally restricted Authors report quantifiable expressing cells in pyramidal layer of hippocampal CA1.
TS24: cerebellum Absent No expression in Purkinje cell layer of cerebellum.

Specimen E18.5 not shown: embryonic day 18.5 (more )
Structure Level Pattern Image Note
TS26: corpus striatum Present Authors report several expressing cells.
TS26: lateral ganglionic eminence Present Authors report several expressing cells.
TS26: hippocampus Present Regionally restricted Authors report several expressing cells in pyramidal layer of hippocampal CA1.
TS26: cerebellum Purkinje cell layer Absent

Specimen P3 not shown: postnatal day 3 (more )
Structure Level Pattern Image Note
TS27: CA1 pyramidal cell layer Present Authors report several expressing cells.
TS27: corpus striatum Present Authors report several expressing cells.
TS27: lateral ganglionic eminence Present Authors report several expressing cells.
TS27: cerebellum Purkinje cell layer Absent

Specimen P7 not shown: postnatal day 7 (more )
Structure Level Pattern Image Note
TS28: CA1 pyramidal cell layer Weak Authors report quantifiable expressing cells.
TS28: corpus striatum Weak Authors report quantifiable expressing cells.
TS28: lateral ganglionic eminence Weak Authors report quantifiable expressing cells.
TS28: cerebellum Purkinje cell layer Trace Authors report very few expressing cells.

Specimen P15 not shown: postnatal day 15 (more )
Structure Level Pattern Image Note
TS28: CA1 pyramidal cell layer Trace Authors report very few expressing cells.
TS28: corpus striatum Trace Authors report very few expressing cells.
TS28: lateral ganglionic eminence Trace Authors report very few expressing cells.
TS28: cerebellum Purkinje cell layer Present Authors report several expressing cells.

Specimen P35 not shown: postnatal day 35 (more )
Structure Level Pattern Image Note
TS28: CA1 pyramidal cell layer Absent
TS28: corpus striatum Absent
TS28: lateral ganglionic eminence Absent
TS28: cerebellum Purkinje cell layer Trace Authors report very few expressing cells.


Contributing Projects:
Mouse Genome Database (MGD), Gene Expression Database (GXD), Mouse Models of Human Cancer database (MMHCdb) (formerly Mouse Tumor Biology (MTB)), Gene Ontology (GO)
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last database update
12/10/2024
MGI 6.24
The Jackson Laboratory