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Gene Expression Data
Assay Details
Assay
Reference: J:158583 Ko HW, et al., Broad-minded links cell cycle-related kinase to cilia assembly and hedgehog signal transduction. Dev Cell. 2010 Feb 16;18(2):237-47
Assay type: Immunohistochemistry
MGI Accession ID: MGI:7380669
Gene symbol: Mnx1
Gene name: motor neuron and pancreas homeobox 1
Antibody: clone 81.5C10
Detection system: Secondary antibody
Results
Specimen 1A HB9 WT: embryonic day 10.5 (more )
Structure Level Pattern Image Note
TS17: neural tube Present Regionally restricted 1A HB9 WT Expression in motoneuron domain.
Specimen 1A HB9 bromi: embryonic day 10.5; Tbc1d32bromi/Tbc1d32bromi (more )
Structure Level Pattern Image Note
TS17: neural tube Present Regionally restricted 1A HB9 bromi Expression ectopically expanded into more ventral regions.
Specimen 3A HB9 WT: embryonic day 10.5 (more )
Structure Level Pattern Image Note
TS17: neural tube Present 3A HB9 WT
Specimen 3A HB9 bromi: embryonic day 10.5; Tbc1d32bromi/Tbc1d32bromi (more )
Structure Level Pattern Image Note
TS17: neural tube Present 3A HB9 bromi
Specimen 3A HB9 Gli3xt: embryonic day 10.5; Gli3Xt-J/Gli3Xt-J (more )
Structure Level Pattern Image Note
TS17: neural tube Present 3A HB9 Gli3xt Authors report normal expression.
Specimen 3A HB9 bromi,Gli3xt: embryonic day 10.5; Gli3Xt-J/Gli3Xt-J, Tbc1d32bromi/Tbc1d32bromi (more )
Structure Level Pattern Image Note
TS17: neural tube Present Regionally restricted 3A HB9 bromi,Gli3xt Authors report disruption of floor plate specification.
Specimen 3B HB9 WT: embryonic day 10.5 (more )
Structure Level Pattern Image Note
TS17: neural tube Present 3B HB9 WT
Specimen 3B HB9 bromi: embryonic day 10.5; Tbc1d32bromi/Tbc1d32bromi (more )
Structure Level Pattern Image Note
TS17: neural tube Present Regionally restricted 3B HB9 bromi
Specimen 3B HB9 Gli2: embryonic day 10.5; Gli2tm1Alj/Gli2tm1Alj (more )
Structure Level Pattern Image Note
TS17: neural tube Present Regionally restricted 3B HB9 Gli2 Ventral neural patterning similar in bromi and Gli2 single mutants
Specimen 3B HB9 bromi,Gli2: embryonic day 10.5; Gli2tm1Alj/Gli2tm1Alj, Tbc1d32bromi/Tbc1d32bromi (more )
Structure Level Pattern Image Note
TS17: neural tube Present 3B HB9 bromi,Gli2
Specimen S4B HB9 WT: embryonic day 10.5 (more )
Structure Level Pattern Image Note
TS17: neural tube Present S4B HB9 Wt
Specimen S4B HB9 RRF/RRF: embryonic day 10.5; Tbc1d32Gt(RRF165)Byg/Tbc1d32Gt(RRF165)Byg (more )
Structure Level Pattern Image Note
TS17: neural tube Present Regionally restricted S4B HB9 RRF/RRF Expression identical to that of bromi mutants.
Contributing Projects:
Mouse Genome Database (MGD), Gene Expression Database (GXD), Mouse Models of Human Cancer database (MMHCdb) (formerly Mouse Tumor Biology (MTB)), Gene Ontology (GO)
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06/12/2024
MGI 6.13 		The Jackson Laboratory