Tg(Nppa-cre)m-3Vmc
Transgene Detail
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| Symbol: |
Tg(Nppa-cre)m-3Vmc |
| Name: |
transgene insertion m-3, Vincent M Christoffels |
| MGI ID: |
MGI:7382834 |
| Synonyms: |
-3mCre |
| Transgene: |
Tg(Nppa-cre)m-3Vmc Location: unknown
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| Alliance: |
Tg(Nppa-cre)m-3Vmc page
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| Strain of Origin: |
Not Specified
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| Transgene Type: |
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Transgenic (Recombinase) |
| Mutation: |
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Insertion
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Tg(Nppa-cre)m-3Vmc expression driven by
1 gene
Transgene expression driven by:
| Organism |
Driver Gene |
Note |
| mouse |
Nppa (MGI:97367) |
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Mutation details: The transgenic construct consists of a sequence fragment encoding a consensus Kozak signal, a nuclear localization signal and cre recombinase inserted at the start codon of the mouse Nppa genomic sequence (-3 kb relative to the transcription start site to upstream of the NRSE (neuron-restrictive silencer element) in the 3' UTR) with human growth hormone gene poly(A) signal sequences added to the 3' end. The 0.7 kb proximal regulatory region, containing the promoter and silencer and enhancer sequences, is included.
(J:278530)
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Activity: |
 Tissue activity of this recombinase allele
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Driver:
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Nppa
(mouse)
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| Mouse strains and cell lines
available from the International Mouse Strain Resource
(IMSR) |
| Carrying this Mutation: |
Mouse Strains: 0 strains available
Cell Lines: 0 lines available
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| Original: |
J:278530 Horsthuis T, et al., Distinct regulation of developmental and heart disease-induced atrial natriuretic factor expression by two separate distal sequences. Circ Res. 2008 Apr 11;102(7):849-59 |
| All: |
1 reference(s) |
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Analysis Tools
