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Gcgtm1.1(cre/ERT2)Yasu
Targeted Allele Detail
Summary
Symbol: Gcgtm1.1(cre/ERT2)Yasu
Name: glucagon; targeted mutation 1.1, Yasuhiro Yamada
MGI ID: MGI:7384334
Synonyms: Gcg-CreERT2
Gene: Gcg  Location: Chr2:62304874-62313994 bp, - strand  Genetic Position: Chr2, 35.85 cM
Alliance: Gcgtm1.1(cre/ERT2)Yasu page
Mutation
origin
Germline Transmission:  Earliest citation of germline transmission: J:330715
Parent Cell Line:  Not Specified (ES Cell)
Strain of Origin:  C57BL/6J
Mutation
description
Allele Type:    Targeted (Inducible, Recombinase)
Inducer:    tamoxifen
Mutation:    Insertion
 
Gcgtm1.1(cre/ERT2)Yasu expression driven by 1 gene
 
Mutation details: The targeting construct inserted an inducible cre/ERT2 fusion gene and rox-flanked selection cassette. Dre-mediated recombination removed the selection cassette. (J:330715)
Recombinase
activity
Activity:
 Tissue activity of this recombinase allele
Driver: Gcg (mouse)
Summary of all recombinase alleles driven by Gcg.
 

Find Mice (IMSR)
Mouse strains and cell lines available from the International Mouse Strain Resource (IMSR)
Carrying this Mutation:  Mouse Strains: 0 strains available      Cell Lines: 0 lines available
Carrying any Gcg Mutation:  34 strains or lines available
References
Original:  J:330715 Hirano M, et al., MYCL-mediated reprogramming expands pancreatic insulin-producing cells. Nat Metab. 2022;4(2):254-268
All:  1 reference(s)
Contributing Projects:
Mouse Genome Database (MGD), Gene Expression Database (GXD), Mouse Models of Human Cancer database (MMHCdb) (formerly Mouse Tumor Biology (MTB)), Gene Ontology (GO)
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Funding Information
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Send questions and comments to User Support. 		last database update
11/19/2024
MGI 6.24 		The Jackson Laboratory