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Gene Expression Data
Assay Details
Assay
Reference: J:186470 Lopes C, et al., Tlx3 and runx1 act in combination to coordinate the development of a cohort of nociceptors, thermoceptors, and pruriceptors. J Neurosci. 2012 Jul 11;32(28):9706-15
Assay type: RNA in situ
MGI Accession ID: MGI:7388624
Gene symbol: Mrgprd
Gene name: MAS-related GPR, member D
Probe: Mrgprd probe1
Probe preparation: Antisense RNA
Results
Specimen 4A Mrgprd Control: postnatal day 30; Tlx3tm2.1Qima/? (more )
Note: Littermate control; genotype either fl/fl or fl/+.
Structure Cell Type Level Pattern Image Note
TS28: lumbar dorsal root ganglion neuron Present Regionally restricted 4A Mrgprd Control Expression in group of polymodal nociceptors representing 30% of total DRG neurons
Specimen 4A Mrgprd Tlx3 CKO: postnatal day 30; Tlx3tm2.1Qima/Tlx3tm2.1Qima, Tg(Scn10a-cre)1Rkun/0 (more )
Note: Conditional mutant.
Structure Level Pattern Image Note
TS28: lumbar dorsal root ganglion Trace 4A Mrgprd Tlx3 CKO Expression greatly reduced but not completely eliminated.
Specimen 5A Mrgprd Control: embryonic day 16.5 (more )
Structure Level Pattern Image Note
TS24: lumbar dorsal root ganglion Present 5A Mrgprd Control
Specimen 5A Mrgprd Tlx3-/-: embryonic day 16.5; Tlx3tm1Sjk/Tlx3tm1Sjk (more )
Structure Level Pattern Image Note
TS24: lumbar dorsal root ganglion Absent 5A Mrgprd Tlx3-/- Expression compltely eliminated.
Contributing Projects:
Mouse Genome Database (MGD), Gene Expression Database (GXD), Mouse Models of Human Cancer database (MMHCdb) (formerly Mouse Tumor Biology (MTB)), Gene Ontology (GO)
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Send questions and comments to User Support. 		last database update
12/10/2024
MGI 6.24 		The Jackson Laboratory