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Gene Expression Data
Assay Details
Assay
Reference: J:186470 Lopes C, et al., Tlx3 and runx1 act in combination to coordinate the development of a cohort of nociceptors, thermoceptors, and pruriceptors. J Neurosci. 2012 Jul 11;32(28):9706-15
Assay type: RNA in situ
MGI Accession ID: MGI:7388630
Gene symbol: Trpa1
Gene name: transient receptor potential cation channel, subfamily A, member 1
Probe: TRPA1 probe1
Probe preparation: Antisense RNA
Results
Specimen cervical DRG not shown: postnatal day 30; Tlx3tm2.1Qima/? (more )
Note: Littermate control; genotype either fl/fl or fl/+.
Structure Level Pattern Image Note
TS28: cervical dorsal root ganglion Strong High level expression enriched in cervical and thoracic DRG.
Specimen thoracic DRG not shown: postnatal day 30; Tlx3tm2.1Qima/? (more )
Note: Littermate control; genotype either fl/fl or fl/+.
Structure Level Pattern Image Note
TS28: thoracic dorsal root ganglion Strong High level expression enriched in cervical and thoracic DRG.
Specimen Tlx3 CKO thoracic DRG not shown: postnatal day 30; Tlx3tm2.1Qima/Tlx3tm2.1Qima, Tg(Scn10a-cre)1Rkun/0 (more )
Note: Conditional mutant.
Structure Level Pattern Image Note
TS28: thoracic dorsal root ganglion Trace Expression in thoracic DGG greatly reduced but not compltely eliminated.
Specimen 4D TRPA1 Control: postnatal day 30; Tlx3tm2.1Qima/? (more )
Note: Littermate control; genotype either fl/fl or fl/+.
Structure Level Pattern Image Note
TS28: lumbar dorsal root ganglion Present 4D TPRA1 Control Lower level of expression compared to cervical and thoracic DRG.
Specimen 4D TRPA1 Tlx3 CKO: postnatal day 30; Tlx3tm2.1Qima/Tlx3tm2.1Qima, Tg(Scn10a-cre)1Rkun/0 (more )
Note: Conditional mutant.
Structure Level Pattern Image Note
TS28: lumbar dorsal root ganglion Absent 4D TPRA1 Tlx3 CKO No expression in lumbar DRG at P30.
Contributing Projects:
Mouse Genome Database (MGD), Gene Expression Database (GXD), Mouse Models of Human Cancer database (MMHCdb) (formerly Mouse Tumor Biology (MTB)), Gene Ontology (GO)
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12/10/2024
MGI 6.24 		The Jackson Laboratory