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Gfralem1(cre)Lbrl
Endonuclease-mediated Allele Detail
Summary
Symbol: Gfralem1(cre)Lbrl
Name: GDNF family receptor alpha like; endonuclease-mediated mutation 1, Stephen Liberles
MGI ID: MGI:7397279
Synonyms: Gfral-p2a-Cre
Gene: Gfral  Location: Chr9:76071389-76120939 bp, - strand  Genetic Position: Chr9, 42.48 cM
Alliance: Gfralem1(cre)Lbrl page
Mutation
origin
Strain of Origin:  C57BL/6J
Mutation
description
Allele Type:    Endonuclease-mediated (Recombinase)
Mutation:    Insertion
 
Gfralem1(cre)Lbrl expression driven by 1 gene
 
Mutation details: Using the CRISPR/Cas9 technology, a p2a-cre cassette was inserted into the 3' UTR of the mouse Gfral locus. (J:307177)
Recombinase
activity
Activity:
 Tissue activity of this recombinase allele
Driver: Gfral (mouse)
Summary of all recombinase alleles driven by Gfral.
 

Find Mice (IMSR)
Mouse strains and cell lines available from the International Mouse Strain Resource (IMSR)
Carrying this Mutation:  Mouse Strains: 0 strains available      Cell Lines: 0 lines available
Carrying any Gfral Mutation:  36 strains or lines available
References
Original:  J:307177 Zhang C, et al., Area Postrema Cell Types that Mediate Nausea-Associated Behaviors. Neuron. 2021 Feb 3;109(3):461-472.e5
All:  2 reference(s)
Contributing Projects:
Mouse Genome Database (MGD), Gene Expression Database (GXD), Mouse Models of Human Cancer database (MMHCdb) (formerly Mouse Tumor Biology (MTB)), Gene Ontology (GO)
Citing These Resources
Funding Information
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Send questions and comments to User Support. 		last database update
10/09/2024
MGI 6.24 		The Jackson Laboratory