Tg(Zbtb7b/CD4-cre/ERT2,-CD2)1Daav
Transgene Detail
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| Symbol: |
Tg(Zbtb7b/CD4-cre/ERT2,-CD2)1Daav |
| Name: |
transgene insertion 1, Dario AA Vignali |
| MGI ID: |
MGI:7414281 |
| Synonyms: |
ThPOKCreERT2.hCD2 |
| Transgene: |
Tg(Zbtb7b/CD4-cre/ERT2,-CD2)1Daav Location: unknown
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| Alliance: |
Tg(Zbtb7b/CD4-cre/ERT2,-CD2)1Daav page
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| Transgene Type: |
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Transgenic (Epitope tag, Inducible, Recombinase) |
| Inducer: |
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tamoxifen |
| Mutation: |
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Insertion
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Tg(Zbtb7b/CD4-cre/ERT2,-CD2)1Daav expression driven by
1 gene
Transgene expression driven by:
| Organism |
Driver Gene |
Note |
| mouse |
Zbtb7b (MGI:102755) |
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Mutation details: A 562base pair fragment of the Zbtb7b silencer sequence was inserted into a mini-transgene containing the minimal Cd4 enhancer-promoter-cre/ERT2. The sequence encoding an internal ribosomal entry site and human CD2 were also inserted downstream of the cDNA cassette encoding cre/ERT2. The transgene expresses Cre specifically in the CD4 lineage. Founder information was not available. Line number 1 was assigned for the transgene inserted into chromosome 1 at approximately 1E3-F.
(J:312516)
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Activity: |
 Tissue activity of this recombinase allele
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Driver:
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Zbtb7b
(mouse)
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| Mouse strains and cell lines
available from the International Mouse Strain Resource
(IMSR) |
| Carrying this Mutation: |
Mouse Strains: 0 strains available
Cell Lines: 0 lines available
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| Original: |
J:312516 Andrews LP, et al., A Cre-driven allele-conditioning line to interrogate CD4(+) conventional T cells. Immunity. 2021 Oct 12;54(10):2209-2217.e6 |
| All: |
1 reference(s) |
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Analysis Tools
