Ccl27al<em1Nax> Endonuclease-mediated Allele Detail MGI Mouse (MGI:7427639)

About Help FAQ

Ccl27al^em1Nax
Endonuclease-mediated Allele Detail

Summary | Mutation origin | Mutation description | Phenotypes | Find Mice (IMSR) | References

Summary

Symbol:	Ccl27al^em1Nax
Name:	C-C motif chemokine ligand 27A like; endonuclease-mediated mutation 1, Na Xiong
MGI ID:	MGI:7427639
Gene:	Ccl27al Location: Chr4:42153436-42158839 bp, + strand Genetic Position: Chr4, 22.29 cM
Alliance:	Ccl27al^em1Nax page

Mutation
origin

Strain of Origin:

Not Specified

Mutation
description

Allele Type:		Endonuclease-mediated (Null/knockout)
Mutation:		Insertion
		Mutation details: CRISPR/Cas9 technology generated a 1 bp insertion. This allele was generated in conjunction with Ccl27a^em1Nax and Ccl27b^em1Nax targeting exon II shared by all three Ccl27 genes. (J:330550)

Phenotypes

View phenotypes and curated references for all genotypes (concatenated display).

Find Mice (IMSR)

Mouse strains and cell lines available from the International Mouse Strain Resource (IMSR)
Carrying this Mutation:	Mouse Strains: 0 strains available Cell Lines: 0 lines available
Carrying any Ccl27al Mutation:	4 strains or lines available

References

Original:	J:330550 Davila ML, et al., CCL27 is a crucial regulator of immune homeostasis of the skin and mucosal tissues. iScience. 2022 Jun 17;25(6):104426
All:	1 reference(s)

Contributing Projects: Mouse Genome Database (MGD), Gene Expression Database (GXD), Mouse Models of Human Cancer database (MMHCdb) (formerly Mouse Tumor Biology (MTB)), Gene Ontology (GO)
Citing These Resources Funding Information Warranty Disclaimer, Privacy Notice, Licensing, & Copyright Send questions and comments to User Support.	last database update 11/19/2024 MGI 6.24