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Gata6tm1(cre/ERT2)Bzsh
Targeted Allele Detail
Summary
Symbol: Gata6tm1(cre/ERT2)Bzsh
Name: GATA binding protein 6; targeted mutation 1, Bin Zhou
MGI ID: MGI:7429141
Synonyms: Gata6-iCreER, Gata6-rox-stop-rox-CreER
Gene: Gata6  Location: Chr18:11052510-11085636 bp, + strand  Genetic Position: Chr18, 5.63 cM
Alliance: Gata6tm1(cre/ERT2)Bzsh page
Mutation
origin
Germline Transmission:  Earliest citation of germline transmission: J:332772
Parent Cell Line:  Not Specified (ES Cell)
Strain of Origin:  Not Specified
Mutation
description
Allele Type:    Targeted (Conditional ready, Inducible, Recombinase)
Inducer:    tamoxifen
Mutation:    Insertion
 
Gata6tm1(cre/ERT2)Bzsh expression driven by 1 gene
 
Mutation details: By conventional homologous recombination using ES cells with neomycin for selection, a rox-stop-rox-CreER-WPRE (Woodchuck hepatitis virus regulatory element)-polyA cassette into the Gata6 gene, replacing the endogenous translational start codon. (J:332772)
Recombinase
activity
Activity:
 Tissue activity of this recombinase allele
Driver: Gata6 (mouse)
Summary of all recombinase alleles driven by Gata6.
 

Find Mice (IMSR)
Mouse strains and cell lines available from the International Mouse Strain Resource (IMSR)
Carrying this Mutation:  Mouse Strains: 0 strains available      Cell Lines: 0 lines available
Carrying any Gata6 Mutation:  35 strains or lines available
References
Original:  J:332772 Jin H, et al., Genetic fate-mapping reveals surface accumulation but not deep organ invasion of pleural and peritoneal cavity macrophages following injury. Nat Commun. 2021 May 17;12(1):2863
All:  1 reference(s)
Contributing Projects:
Mouse Genome Database (MGD), Gene Expression Database (GXD), Mouse Models of Human Cancer database (MMHCdb) (formerly Mouse Tumor Biology (MTB)), Gene Ontology (GO)
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Funding Information
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Send questions and comments to User Support. 		last database update
11/12/2024
MGI 6.24 		The Jackson Laboratory