About   Help   FAQ
Gene Expression Data
Assay Details
Assay
Reference: J:195652 Manso AM, et al., Talin1 has unique expression versus talin 2 in the heart and modifies the hypertrophic response to pressure overload. J Biol Chem. 2013 Feb 8;288(6):4252-64
Assay type: Immunohistochemistry
MGI Accession ID: MGI:7431101
Gene symbol: Tln1
Gene name: talin 1
Antibody: anti-Talin-1 (97H6)
Detection system: Secondary antibody coupled to Alexa Fluor 488
Results
Specimen 1B Tln1: embryonic day 9.0 (more )
Note: Double labeled: green - Tln1; red - Ttn (assay MGI:7431103).
Structure Cell Type Level Pattern Image Note
TS14: cardiac muscle tissue cardiac muscle cell Present 1B Tln1+Titin , 1B Tln1+Titin (inset) , 1B Tln1 Expression in cardiomyocytes, co-localized with Ttn expression.
Specimen 1C Tln1: embryonic day 10.0 (more )
Note: Double labeled: green - Tln1; red - Pecam1 (assay MGI:7431104).
Structure Cell Type Level Pattern Image Note
TS16: heart cardiac endothelial cell Present 1C Tln1 , 1C Tln1+PECAM
Specimen 2Ab,c: postnatal adult (more )
Note: Double labeled: green - Tln1; red - Dys (Dmd assay MGI:7431105).
Structure Cell Type Level Pattern Image Note
TS28: cardiac muscle tissue cardiac muscle cell Trace Regionally restricted 2Ab , 2Ac Minimal expression in cardiomyocytes. Expression not detected in cardiomyocyte membrane.
Specimen 2Ae,f: postnatal adult (more )
Note: Double labeled: green - Tln1; red - Pecam1 (assay MGI:7431104).
Structure Cell Type Level Pattern Image Note
TS28: heart cardiac endothelial cell Present 2Af , 2Ae Expression only in endothelial cells.
Contributing Projects:
Mouse Genome Database (MGD), Gene Expression Database (GXD), Mouse Models of Human Cancer database (MMHCdb) (formerly Mouse Tumor Biology (MTB)), Gene Ontology (GO)
Citing These Resources
Funding Information
Warranty Disclaimer, Privacy Notice, Licensing, & Copyright
Send questions and comments to User Support. 		last database update
12/17/2024
MGI 6.24 		The Jackson Laboratory