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Synbem1(cre)Mdf
Endonuclease-mediated Allele Detail
Summary
Symbol: Synbem1(cre)Mdf
Name: syncytin b; endonuclease-mediated mutation 1, Mark D Fleming
MGI ID: MGI:7433162
Synonyms: SynbCre
Gene: Synb  Location: Chr14:69526793-69531748 bp, - strand  Genetic Position: Chr14, 36.04 cM
Alliance: Synbem1(cre)Mdf page
Mutation
origin
Strain of Origin:  FVB/NJ
Mutation
description
Allele Type:    Endonuclease-mediated (Recombinase)
Mutation:    Insertion
 
Synbem1(cre)Mdf expression driven by 1 gene
 
Mutation details: Using CRISPR targeting, 2A (P2A) and Cre were inserted immediately before the stop codon of the Synb gene. (J:331974)
Recombinase
activity
Activity:
 Tissue activity of this recombinase allele
Driver: Synb (mouse)
Summary of all recombinase alleles driven by Synb.
 

Find Mice (IMSR)
Mouse strains and cell lines available from the International Mouse Strain Resource (IMSR)
Carrying this Mutation:  Mouse Strains: 1 strain available      Cell Lines: 0 lines available
Carrying any Synb Mutation:  7 strains or lines available
References
Original:  J:331974 Cao C, et al., Loss of the placental iron exporter ferroportin 1 causes embryonic demise in late-gestation mouse pregnancy. Development. 2022 Dec 1;149(23):dev201160
All:  1 reference(s)
Contributing Projects:
Mouse Genome Database (MGD), Gene Expression Database (GXD), Mouse Models of Human Cancer database (MMHCdb) (formerly Mouse Tumor Biology (MTB)), Gene Ontology (GO)
Citing These Resources
Funding Information
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Send questions and comments to User Support. 		last database update
11/12/2024
MGI 6.24 		The Jackson Laboratory