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Chatem1(flp)Lowl
Endonuclease-mediated Allele Detail
Summary
Symbol: Chatem1(flp)Lowl
Name: choline O-acetyltransferase; endonuclease-mediated mutation 1,Bradford B Lowell
MGI ID: MGI:7434545
Synonyms: Chat-p2a-Flp
Gene: Chat  Location: Chr14:32130160-32187866 bp, - strand  Genetic Position: Chr14, 19.4 cM
Alliance: Chatem1(flp)Lowl page
Mutation
origin
Strain of Origin:  FVB
Mutation
description
Allele Type:    Endonuclease-mediated (Recombinase)
Mutation:    Insertion
 
Chatem1(flp)Lowl expression driven by 1 gene
 
Mutation details: Using the CRISPR method, the p2a-Flp cassette, flanked by 100-base homology arms both up- and downstream of the Chat stop codon (J:333138)
Recombinase
activity
Activity:
 Tissue activity of this recombinase allele
Driver: Chat (mouse)
Summary of all recombinase alleles driven by Chat.
 

Find Mice (IMSR)
Mouse strains and cell lines available from the International Mouse Strain Resource (IMSR)
Carrying this Mutation:  Mouse Strains: 0 strains available      Cell Lines: 0 lines available
Carrying any Chat Mutation:  57 strains or lines available
References
Original:  J:333138 Coverdell TC, et al., Genetic encoding of an esophageal motor circuit. Cell Rep. 2022 Jun 14;39(11):110962
All:  1 reference(s)
Contributing Projects:
Mouse Genome Database (MGD), Gene Expression Database (GXD), Mouse Models of Human Cancer database (MMHCdb) (formerly Mouse Tumor Biology (MTB)), Gene Ontology (GO)
Citing These Resources
Funding Information
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Send questions and comments to User Support. 		last database update
08/02/2024
MGI 6.24 		The Jackson Laboratory