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Tg(Mobp-icre/ERT2)8Dbe
Transgene Detail
Summary
Symbol: Tg(Mobp-icre/ERT2)8Dbe
Name: transgene insertion 8, Dwight E Bergles
MGI ID: MGI:7434619
Synonyms: Mobp-iCreER
Transgene: Tg(Mobp-icre/ERT2)8Dbe  Location: unknown  
Alliance: Tg(Mobp-icre/ERT2)8Dbe page
Transgene
origin
Strain of Origin:  C57BL/6
Transgene
description
Transgene Type:    Transgenic (Inducible, Recombinase)
Inducer:    tamoxifen
Mutation:    Insertion
 
Tg(Mobp-icre/ERT2)8Dbe expression driven by 1 gene
 
Mutation details: The iCreERT2 sequence was inserted into pBACe3.6_RP23-127H7. Five founders were analyzed. Lines 8 and 16 with the highest tamoxifen-dependent recombination efficiency were selected and maintained as conditional cre lines. (J:333154)
Recombinase
activity
Activity:
 Tissue activity of this recombinase allele
Driver: Mobp (mouse)
Summary of all recombinase alleles driven by Mobp.
 

Find Mice (IMSR)
Mouse strains and cell lines available from the International Mouse Strain Resource (IMSR)
Carrying this Mutation:  Mouse Strains: 0 strains available      Cell Lines: 0 lines available
References
Original:  J:333154 Heo D, et al., Stage-specific control of oligodendrocyte survival and morphogenesis by TDP-43. Elife. 2022 Mar 21;11:e75230
All:  1 reference(s)
Contributing Projects:
Mouse Genome Database (MGD), Gene Expression Database (GXD), Mouse Models of Human Cancer database (MMHCdb) (formerly Mouse Tumor Biology (MTB)), Gene Ontology (GO)
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Funding Information
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Send questions and comments to User Support. 		last database update
11/12/2024
MGI 6.24 		The Jackson Laboratory