Lepr<em4(dre/ERT2)Smoc> Endonuclease-mediated Allele Detail MGI Mouse (MGI:7434946)

Lepr^{em4(dre/ERT2)Smoc}
Endonuclease-mediated Allele Detail

Summary

Symbol:	Lepr^{em4(dre/ERT2)Smoc}
Name:	leptin receptor; endonuclease-mediated mutation 4, Shanghai Model Organisms Center
MGI ID:	MGI:7434946
Synonyms:	Lepr^dreER
Gene:	Lepr Location: Chr4:101574601-101672549 bp, + strand Genetic Position: Chr4, 46.96 cM
Alliance:	Lepr^{em4(dre/ERT2)Smoc} page

Mutation
origin

Strain of Origin:

Not Specified

Mutation
description

Allele Type:

Endonuclease-mediated (Inducible, Recombinase)

Inducer:

tamoxifen

Mutation:

Insertion

Lepr^{em4(dre/ERT2)Smoc} expression driven by 1 gene

The allele was generated by inserting the dreER sequence into the endogenous Lepr gene locus. (J:333183)

Recombinase
activity

Activity:	Tissue activity of this recombinase allele
Driver:	Lepr (mouse) Summary of all recombinase alleles driven by Lepr. Comparative matrix view of recombinase activities Alliance mouse Lepr gene page

Find Mice (IMSR)

Mouse strains and cell lines available from the International Mouse Strain Resource (IMSR)
Carrying this Mutation:	Mouse Strains: 0 strains available Cell Lines: 0 lines available
Carrying any Lepr Mutation:	120 strains or lines available

References

Original:	J:333183 Shu HS, et al., Tracing the skeletal progenitor transition during postnatal bone formation. Cell Stem Cell. 2021 Dec 2;28(12):2122-2136.e3
All:	1 reference(s)

Contributing Projects: Mouse Genome Database (MGD), Gene Expression Database (GXD), Mouse Models of Human Cancer database (MMHCdb) (formerly Mouse Tumor Biology (MTB)), Gene Ontology (GO)
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