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Actbem1(tetO-cre)Ttaka
Endonuclease-mediated Allele Detail
Summary
Symbol: Actbem1(tetO-cre)Ttaka
Name: actin, beta; endonuclease-mediated mutation 1, Takeshi Takarada
MGI ID: MGI:7434981
Synonyms: TRE-PA-Cre
Gene: Actb  Location: Chr5:142888870-142892509 bp, - strand  Genetic Position: Chr5, 81.8 cM
Alliance: Actbem1(tetO-cre)Ttaka page
Mutation
origin
Strain of Origin:  C57BL/6J
Mutation
description
Allele Type:    Endonuclease-mediated (Recombinase)
Mutation:    Insertion
 
Actbem1(tetO-cre)Ttaka expression driven by 1 gene
 
Mutation details: CRISPR-targeting introduced a tetracycline promoter driving inducible expression of the cre recombinase gene. (J:291642)
Recombinase
activity
Activity:
 Tissue activity of this recombinase allele
Driver: tetO (bacteria)
Summary of all recombinase alleles driven by tetO.
 

Find Mice (IMSR)
Mouse strains and cell lines available from the International Mouse Strain Resource (IMSR)
Carrying this Mutation:  Mouse Strains: 0 strains available      Cell Lines: 0 lines available
Carrying any Actb Mutation:  53 strains or lines available
References
Original:  J:291642 Takao T, et al., Establishment of a tTA-dependent photoactivatable Cre recombinase knock-in mouse model for optogenetic genome engineering. Biochem Biophys Res Commun. 2020 May 21;526(1):213-217
All:  1 reference(s)
Contributing Projects:
Mouse Genome Database (MGD), Gene Expression Database (GXD), Mouse Models of Human Cancer database (MMHCdb) (formerly Mouse Tumor Biology (MTB)), Gene Ontology (GO)
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Funding Information
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Send questions and comments to User Support. 		last database update
11/19/2024
MGI 6.24 		The Jackson Laboratory