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Ebf3tm1.1(cre/ERT2)Tng
Targeted Allele Detail
Summary
Symbol: Ebf3tm1.1(cre/ERT2)Tng
Name: early B cell factor 3; targeted mutation 1.1, Takashi Nagasawa
MGI ID: MGI:7435191
Synonyms: Ebf3-CreERT2
Gene: Ebf3  Location: Chr7:136795402-136916174 bp, - strand  Genetic Position: Chr7, 82.26 cM, cytoband F3-F4
Alliance: Ebf3tm1.1(cre/ERT2)Tng page
Mutation
origin
Germline Transmission:  Earliest citation of germline transmission: J:271945
Parent Cell Line:  KY1.1 (ES Cell)
Strain of Origin:  (C57BL/6J x 129S6/SvEvTac)F1
Mutation
description
Allele Type:    Targeted (Recombinase)
Mutation:    Insertion
 
Ebf3tm1.1(cre/ERT2)Tng expression driven by 1 gene
 
Mutation details: The targeting construct inserted at the STOP codon in exon 16 an IRES, cre recombinase fused to ERT2 and FRT-flanked neomycin resistance cassette. Flp-mediated recombination removed the selection cassette. (J:271945)
Recombinase
activity
Activity:
 Tissue activity of this recombinase allele
Driver: Ebf3 (mouse)
Summary of all recombinase alleles driven by Ebf3.
 

Find Mice (IMSR)
Mouse strains and cell lines available from the International Mouse Strain Resource (IMSR)
Carrying this Mutation:  Mouse Strains: 0 strains available      Cell Lines: 0 lines available
Carrying any Ebf3 Mutation:  36 strains or lines available
References
Original:  J:271945 Seike M, et al., Stem cell niche-specific Ebf3 maintains the bone marrow cavity. Genes Dev. 2018 Mar 1;32(5-6):359-372
All:  1 reference(s)
Contributing Projects:
Mouse Genome Database (MGD), Gene Expression Database (GXD), Mouse Models of Human Cancer database (MMHCdb) (formerly Mouse Tumor Biology (MTB)), Gene Ontology (GO)
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Send questions and comments to User Support. 		last database update
08/02/2024
MGI 6.24 		The Jackson Laboratory