About   Help   FAQ
Sfrp5tm1.1(cre)Kkb
Targeted Allele Detail
Summary
Symbol: Sfrp5tm1.1(cre)Kkb
Name: secreted frizzled-related sequence protein 5; targeted mutation 1.1, Hiroki Kokubo
MGI ID: MGI:7437537
Synonyms: Sfrp5-Cre
Gene: Sfrp5  Location: Chr19:42186410-42190691 bp, - strand  Genetic Position: Chr19, 35.93 cM, cytoband D1
Alliance: Sfrp5tm1.1(cre)Kkb page
Mutation
origin
Germline Transmission:  Earliest citation of germline transmission: J:245018
Parent Cell Line:  Not Specified (ES Cell)
Strain of Origin:  Not Specified
Mutation
description
Allele Type:    Targeted (Recombinase)
Mutations:    Insertion, Intragenic deletion
 
Sfrp5tm1.1(cre)Kkb expression driven by 1 gene
 
Mutation details: A targeting vector consist of a cassette containing Cre-recombinase genes with frt-PGK-neomycin (neo)-bpA-frt was used for homologous recombination to replace the exon 1 of the Sfrp5 gene in ES cells. Frt-neo was then removed by crossing with Rosa-Flp mice. (J:245018)
Recombinase
activity
Activity:
 Tissue activity of this recombinase allele
Driver: Sfrp5 (mouse)
Summary of all recombinase alleles driven by Sfrp5.
 

Find Mice (IMSR)
Mouse strains and cell lines available from the International Mouse Strain Resource (IMSR)
Carrying this Mutation:  Mouse Strains: 1 strain available      Cell Lines: 0 lines available
Carrying any Sfrp5 Mutation:  27 strains or lines available
References
Original:  J:245018 Fujii M, et al., Sfrp5 identifies murine cardiac progenitors for all myocardial structures except for the right ventricle. Nat Commun. 2017 Mar 13;8:14664
All:  2 reference(s)
Contributing Projects:
Mouse Genome Database (MGD), Gene Expression Database (GXD), Mouse Models of Human Cancer database (MMHCdb) (formerly Mouse Tumor Biology (MTB)), Gene Ontology (GO)
Citing These Resources
Funding Information
Warranty Disclaimer, Privacy Notice, Licensing, & Copyright
Send questions and comments to User Support. 		last database update
11/12/2024
MGI 6.24 		The Jackson Laboratory