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Hopxtm4.1(cre)Joe
Targeted Allele Detail
Summary
Symbol: Hopxtm4.1(cre)Joe
Name: HOP homeobox; targeted mutation 4.1, Jonathan A Epstein
MGI ID: MGI:7437591
Synonyms: HopxCre
Gene: Hopx  Location: Chr5:77234835-77262968 bp, - strand  Genetic Position: Chr5, 41.45 cM
Alliance: Hopxtm4.1(cre)Joe page
Mutation
origin
Germline Transmission:  Earliest citation of germline transmission: J:245319
Parent Cell Line:  Not Specified (ES Cell)
Strain of Origin:  Not Specified
Mutation
description
Allele Type:    Targeted (Recombinase, Reporter)
Mutation:    Insertion
 
Hopxtm4.1(cre)Joe expression driven by 1 gene
 
Mutation details: An IRES-eGFP-cre-Frt-PGK-neo-Frt cassette was inserted into the 3' UTR of the Hopx locus by homologous recombination in ES cells. Subsequently, these animals were crossed to mice expressing the FLPe recombinase to remove the PGK-neo cassette. (J:245319)
Recombinase
activity
Activity:
 Tissue activity of this recombinase allele
Driver: Hopx (mouse)
Summary of all recombinase alleles driven by Hopx.
 

Find Mice (IMSR)
Mouse strains and cell lines available from the International Mouse Strain Resource (IMSR)
Carrying this Mutation:  Mouse Strains: 0 strains available      Cell Lines: 0 lines available
Carrying any Hopx Mutation:  11 strains or lines available
References
Original:  J:245319 Jain R, et al., HEART DEVELOPMENT. Integration of Bmp and Wnt signaling by Hopx specifies commitment of cardiomyoblasts. Science. 2015 Jun 26;348(6242):aaa6071
All:  1 reference(s)
Contributing Projects:
Mouse Genome Database (MGD), Gene Expression Database (GXD), Mouse Models of Human Cancer database (MMHCdb) (formerly Mouse Tumor Biology (MTB)), Gene Ontology (GO)
Citing These Resources
Funding Information
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Send questions and comments to User Support. 		last database update
11/19/2024
MGI 6.24 		The Jackson Laboratory